Publication Name	World Journal of Gastroenterology
Manuscript ID	19791
Country	Serbia

Received	2015-05-21 08:31
Peer-Review Started	2015-05-22 09:58
To Make the First Decision	2015-06-23 15:15
Return for Revision	2015-06-27 16:54
Revised	2015-07-16 01:25
Second Decision	2015-09-13 22:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-22 09:41
Articles in Press	2015-09-22 09:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-20 21:57
Publish the Manuscript Online	2015-11-03 17:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Role of Helicobacter pylori infection in gastric carcinogenesis: Current knowledge and future directions
Manuscript Source	Invited Manuscript
All Author List	Aleksandra Sokic-Milutinovic, Tamara Alempijevic and Tomica Milosavljevic
Funding Agency and Grant Number
Corresponding Author	Aleksandra Sokic-Milutinovic, MD, PhD, Professor, Clinic for Gastroenterology and Hepatology, Clinical Center of Serbia and School of Medicine University of Belgrade, Koste Todorovica 6, 11000 Belgrade, Serbia. asokicmilutinovic@gmail.com
Key Words	Helicobacter pylori; Gastric cancer; Vaccine; Eradication therapy; Prevention
Core Tip	Two main therapeutic strategies could reduce the incidence of Helicobacter pylori (H. pylori)-related gastric cancer: eradication of the infection or vaccination. Success of a gastric cancer prevention strategy depends on the eradication of the infection or on vaccination before irreversible mucosal changes (severe atrophy, intestinal metaplasia or dysplasia) have occurred. Eradication therapy results are sub?optimal due to increased antibiotic resistance in H. pylori and patient noncompliance. To improve the rates of eradication, rescue regimens have been developed. Concomitant and sequential protocols seem equally effective rescue strategies. An effective vaccine is not available at present, in spite of enormous effort by different researchers.
Publish Date	2015-11-03 17:31
Citation	Sokic-Milutinovic A, Alempijevic T, Milosavljevic T. Role of Helicobacter pylori infection in gastric carcinogenesis: Current knowledge and future directions. World J Gastroenterol 2015; 21(41): 11654-11672
URL	http://www.wjgnet.com/1007-9327/full/v21/i41/11654.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i41.11654

Full Article (PDF)	WJG-21-11654.pdf
Full Article (Word)	WJG-21-11654.doc
Manuscript File	19791-Review.docx
Answering Reviewers	19791-Answering reviewers.pdf
Audio Core Tip	19791-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	19791-Conflict-of-interest statement.pdf
Copyright License Agreement	19791-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	19791-Language certificate.pdf
Peer-review Report	19791-Peer-review(s).pdf
Scientific Misconduct Check	19791-Scientific misconduct check.pdf
Scientific Editor Work List	19791-Scientific editor work list.pdf