Publication Name	World Journal of Critical Care Medicine
Manuscript ID	22872
Country	United Kingdom

Received	2015-09-29 08:42
Peer-Review Started	2015-10-02 15:09
To Make the First Decision	2015-10-27 11:30
Return for Revision	2015-11-04 15:42
Revised	2015-12-01 20:08
Second Decision	2015-12-28 14:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-01-11 15:50
Articles in Press	2016-01-11 15:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-15 08:27
Publish the Manuscript Online

ISSN	2220-3141(online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Critical Care Medicine
Manuscript Type	Review
Article Title	Neuroprotective measures in children with traumatic brain injury
Manuscript Source	Invited Manuscript
All Author List	Shruti Agrawal and Ricardo Garcia Branco
Funding Agency and Grant Number
Corresponding Author	Shruti Agrawal, MD, FRCPCH, FFICM, Department of Paediatric Intensive Care, Cambridge University Hospitals NHS Foundation Trust, Box 7, Addenbrookes Hospital, Hills Road, Cambridge CB2 0QQ, United Kingdom. shruti.agrawal@addenbrookes.nhs.uk
Key Words	Paediatrics; Traumatic brain injury; Neuroprotection; Intracranial pressure; Paediatric critical care; Advanced neuromonitoring
Core Tip	Paediatric traumatic brain injury (TBI) causes significant morbidity and mortality. The modern management of severe TBI in children focuses on preventing secondary brain injury to improve outcome. In this article, we review the current management of severe TBI in children. We also review the recent advances in understanding intracranial physiology and neuroprotective therapies, advanced and multi-modal neuromonitoring, and potential new therapeutic and prognostic targets.
Publish Date
Citation	Agrawal S, Branco RG. Neuroprotective measures in children with traumatic brain injury. World J Crit Care Med 2016; 5(1): 36-46
URL	http://www.wjgnet.com/2220-3141/full/v5/i1/36.htm
DOI	http://dx.doi.org/10.5492/wjccm.v5.i1.36

Full Article (PDF)	WJCCM-5-36.pdf
Full Article (Word)	WJCCM-5-36.doc
Manuscript File	22872-Review.docx
Answering Reviewers	22872-Answering reviewers.pdf
Audio Core Tip	22872-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	22872-Conflict-of-interest statement.pdf
Copyright License Agreement	22872-Copyright assignment.pdf
Peer-review Report	22872-Peer-review(s).pdf
Scientific Misconduct Check	22872-Scientific misconduct check.pdf
Scientific Editor Work List	22872-Scientific editor work list.pdf