| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Characteristics and outcomes of chronic liver disease patients with acute deteriorated liver function by severity of underlying liver disease
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Yun Soo Hong, Dong Hyun Sinn, Geum-Youn Gwak, Juhee Cho, Danbee Kang, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh and Seung Woon Paik |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Geum-Youn Gwak, MD, PhD, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-Gu, Seoul 06351, South Korea. gy.gwak@samsung.com |
| Key Words |
Acute-on chronic liver failure; Classification; Injury; Organ failure; Survival |
| Core Tip |
Controversy exists over defining acute on chronic liver failure (ACLF). Recently, multimodal ACLF classification that classifies patients into chronic hepatitis, cirrhosis and cirrhosis with previous decompensation has been suggested. We found that the new ACLF classification has clear differences in predisposition, type of injury, accompanying organ failure and long-term outcome by subtype. ACLF patients showed similar high short-term mortality, especially without liver transplantation, according to the subtype, but showed clear difference in the long-term mortality, indicating that the subtyping of ACLF by severity of underlying liver disease is useful. |
| Publish Date |
2016-03-29 15:29 |
| Citation |
Hong YS, Sinn DH, Gwak GY, Cho J, Kang D, Paik YH, Choi MS, Lee JH, Koh KC, Paik SW. Characteristics and outcomes of chronic liver disease patients with acute deteriorated liver function by severity of underlying liver disease. World J Gastroenterol 2016; 22(14): 3785-3792 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i14/3785.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i14.3785 |
