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Articles Published Processes
4/19/2016 9:45:00 AM | Browse: 1017 | Download: 2008
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Received |
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2016-01-14 09:15 |
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Peer-Review Started |
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2016-01-16 16:38 |
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To Make the First Decision |
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2016-01-28 14:22 |
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Return for Revision |
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2016-01-30 11:20 |
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Revised |
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2016-02-09 20:01 |
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Second Decision |
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2016-03-04 18:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2016-03-14 09:40 |
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Articles in Press |
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2016-03-14 09:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-03-29 15:58 |
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Publish the Manuscript Online |
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2016-04-19 09:42 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Influence of antibiotic-regimens on intensive-care unit-mortality and liver-cirrhosis as risk factor
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mireen Friedrich-Rust, Beate Wanger, Florian Heupel, Natalie Filmann, Reinhard Brodt, Volkhard AJ Kempf, Johanna Kessel, Thomas A Wichelhaus, Eva Herrmann, Stefan Zeuzem and Joerg Bojunga |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Mireen Friedrich-Rust, professor, Department of Internal Medicine I (Gastroenterology, Pulmonology, Endocrinology), J.W. Goethe-University Hospital, Theodor-Stern-Kai 7, 60590 Frankfurt am Main,
Germany. mireen.friedrich-rust@kgu.de
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| Key Words |
Intensive care unit; sepsis-bundle; early goal-directed therapy; liver cirrhosis; mortality |
| Core Tip |
This is a retrospective study evaluating the association of appropriate and inappropriate anti-microbial therapy on intensive care unit-mortality with special focus on patients with liver cirrhosis. Charts of 1979 patients were available for analysis. Patients with infection had significantly increased in-hospital mortality. Only 9% of patients with infection received inappropriate initial antimicrobial therapy. Multiresistant bacteria were detected in 23% of patients with infection and were associated with increased mortality. Infection increased mortality 2.24-fold in patients with cirrhosis. Patients with liver cirrhosis were at an increased risk to receive inappropriate initial antimicrobial therapy.
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| Publish Date |
2016-04-19 09:42 |
| Citation |
Friedrich-Rust M, Wanger B, Heupel F, Filmann N, Brodt R, Kempf VAJ, Kessel J, Wichelhaus TA, Herrmann E, Zeuzem S, Bojunga J. Influence of antibiotic-regimens on intensive-care unit-mortality and liver-cirrhosis as risk factor. World J Gastroenterol 2016; 22(16): 4201-4210 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i16/4201.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i16.4201 |
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