Publication Name	World Journal of Gastroenterology
Manuscript ID	2475
Country	Italy

Received	2013-02-25 09:06
Peer-Review Started	2013-02-26 09:00
To Make the First Decision	2013-03-18 15:34
Return for Revision	2013-03-19 14:29
Revised
Second Decision	2013-05-18 16:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-05-19 23:55
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-23 17:21
Publish the Manuscript Online	2013-09-14 11:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	5-ASA colonic mucosal concentrations resulting from different pharmaceutical formulations in ulcerative colitis
Manuscript Source	Invited Manuscript
All Author List	Renata D’Incà, Martina Paccagnella, Romilda Cardin, Surajit Pathak, Vincenzo Baldo, Maria Cecilia Giron and Giacomo Carlo Sturniolo
Funding Agency and Grant Number
Corresponding Author	Dr. Renata D’Incà, Division of Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, VI piano Monoblocco, Via Giustiniani 2, 35127 Padova, Italy. dinca@unipd.it
Key Words	5-aminosalicylic acid; Inflammatory bowel diseases; Mucosal concentration
Core Tip	We report on the concentrations of 5-aminosalicylic acid in the colonic mucosa of ulcerative colitis patients. Significant variations in concentration were observed that were dependent on the type of pharmaceutical formulation and the presence of active disease. Combined oral and topical therapy yielded higher tissue mesalamine concentrations. These differences should be taken into account in treatment strategies, especially in view of the fact that mesalamine can induce mucosal healing in ulcerative colitis.
Publish Date	2013-09-14 11:17
Citation	D’Incà R, Paccagnella M, Cardin R, Pathak S, Baldo V, Giron MC, Sturniolo GC. 5-ASA colonic mucosal concentrations resulting from different pharmaceutical formulations in ulcerative colitis. World J Gastroenterol 2013; 19(34): 5665-5670
URL	http://www.wjgnet.com/1007-9327/full/v19/i34/5665.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i34.5665

Full Article (PDF)	WJG-19-5665.pdf
Manuscript File	2475-Review.docx
Answering Reviewers	2475-Answering reviewers.docx
Copyright License Agreement	2475-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	2475-Language certificate.pdf
Peer-review Report	2475-Peer review(s).pdf
Scientific Editor Work List	2475-Scientific editor work list.doc