Publication Name	World Journal of Gastroenterology
Manuscript ID	25363
Country	Malaysia

Received	2016-03-06 19:56
Peer-Review Started	2016-03-08 08:18
First Decision by Editorial Office Director
Return for Revision	2016-04-14 17:26
Revised	2016-08-31 10:30
Publication Fee Transferred
Second Decision by Editor	2016-09-21 17:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2016-10-19 17:28
Articles in Press	2016-10-19 17:28
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-14 18:39
Publish the Manuscript Online	2016-12-26 19:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Variable outcome in infantile-onset inflammatory bowel disease in an Asian cohort
Manuscript Source	Unsolicited Manuscript
All Author List	Way Seah Lee, Ruey Terng Ng, Koon-Wing Chan and Yu-Lung Lau
Funding Agency and Grant Number
Corresponding Author	Dr. Way Seah Lee, Professor, Department of Paediatrics, University Malaya Medical Center, Lembah Pantai, Kuala Lumpur 59100, Malaysia. leews@um.edu.my
Key Words	Infantile-onset inflammatory bowel disease; Pediatric
Core Tip	We described the clinical features, outcome and role of mutation in IL-10 and IL-10R in Asian children with infantile-onset inflammatory bowel disease (IO-IBD). We reviewed all cases of IO-IBD, defined as onset of disease before 12 mo of age, seen at a single center in Malaysia. We conclude that the clinical features of IO-IBD in this Asian cohort of children were variable. IO-IBD achieved remission at a similar rate, were more likely to discontinue immunosuppression therapy at final review and not more likely to require biologics therapy or surgery.
Publish Date	2016-12-26 19:13
Citation	Lee WS, Ng RT, Chan KW, Lau YL. Variable outcome in infantile-onset inflammatory bowel disease in an Asian cohort. World J Gastroenterol 2016; 22(48): 10653-10662
URL	http://www.wjgnet.com/1007-9327/full/v22/i48/10653.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i48.10653

Full Article (PDF)	WJG-22-10653.pdf
Full Article (Word)	WJG-22-10653.doc
Manuscript File	25363-Review.docx
Answering Reviewers	25363-Answering reviewers.pdf
Audio Core Tip	25363-Audio core tip.m4a
Copyright License Agreement	25363-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	25363-Institutional review board statement.pdf
Supplementary Material	25363-Supplementary material.docx
Peer-review Report	25363-Peer-review(s).pdf
Scientific Misconduct Check	25363-Scientific misconduct check.pdf
Scientific Editor Work List	25363-Scientific editor work list.pdf