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9/1/2016 9:16:00 AM | Browse: 850 | Download: 1105
Publication Name World Journal of Nephrology
Manuscript ID 25453
Country/Territory United Kingdom
Received
2016-03-17 09:41
Peer-Review Started
2016-03-18 17:41
To Make the First Decision
2016-04-15 08:19
Return for Revision
2016-04-18 17:30
Revised
2016-05-02 10:33
Second Decision
2016-06-27 17:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-07-13 13:56
Articles in Press
2016-07-13 13:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-08-26 15:38
Publish the Manuscript Online
2016-09-01 09:16
ISSN 2220-6124 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Observational Study
Article Title Is overhydration in peritoneal dialysis patients associated with cardiac mortality that might be reversible?
Manuscript Source Invited Manuscript
All Author List Elizabeth Oei, Klara Paudel, Annemarie Visser, Hazel Finney and Stanley L Fan
Funding Agency and Grant Number
Corresponding Author Dr. Stanley L Fan, Department of Renal Medicine and Transplantation, Barts Health NHS Trust, Whitechapel Road, Whitechapel, London E1 1BB, United Kingdom. s.fan@qmul.ac.uk
Key Words Bioimpedance; Fluid status; Peritoneal dialysis; Mortality; Overhydration; Cardiac troponin
Core Tip Overhydration measured by bioimpedance spectroscopy is an independent predictor of death in peritoneal dialysis patients. Most studies on this topic provide only a single baseline bioimpedance assessment. We present longitudinal data showing increased cardiac mortality in overhydrated patients, and significant correlation of overhydration with cardiac troponin-T (cTnT) levels. Over 6 mo, these patients had a mean of 7.4 body composition monitor readings and 3.4 cTnT assessments. Patients whose hydration status improved showed a corresponding improvement in cTnT. While observational studies cannot define causality, our results show overhydration is associated with cardiac mortality, and suggest overhydration may be a reversible risk factor.
Publish Date 2016-09-01 09:16
Citation Oei E, Paudel K, Visser A, Finney H, Fan SL. Is overhydration in peritoneal dialysis patients associated with cardiac mortality that might be reversible? World J Nephrol 2016; 5(5): 448-454
URL http://www.wjgnet.com/2220-6124/full/v5/i5/448.htm
DOI http://dx.doi.org/10.5527/wjn.v5.i5.448
Full Article (PDF) WJN-5-448.pdf
Full Article (Word) WJN-5-448.doc
Manuscript File 25453-Review.docx
Answering Reviewers 25453-Answering reviewers.pdf
Audio Core Tip 25453-Audio core tip.mp3
Biostatistics Review Certificate Biostatistics_Statement_20160316210131.docx
Conflict-of-Interest Disclosure Form 25453-Conflict-of-interest statement.pdf
Copyright License Agreement 25453-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20160316210142.docx
Institutional Review Board Approval Form or Document 25453-Institutional review board statement.pdf
Peer-review Report 25453-Peer-review(s).pdf
Scientific Misconduct Check 25453-Scientific misconduct check.pdf
Scientific Editor Work List 25453-Scientific editor work list.pdf