Publication Name	World Journal of Gastroenterology
Manuscript ID	26049
Country	India

Received	2016-03-28 08:58
Peer-Review Started	2016-03-29 13:57
To Make the First Decision	2016-05-12 15:31
Return for Revision	2016-05-13 15:10
Revised	2016-06-22 12:37
Second Decision	2016-07-21 18:37
Accepted by Journal Editor-in-Chief	2016-07-23 17:53
Accepted by Executive Editor-in-Chief	2016-08-01 15:49
Articles in Press	2016-08-01 15:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-24 16:42
Publish the Manuscript Online	2016-09-14 19:04

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Portal biliopathy
Manuscript Source	Invited Manuscript
All Author List	Mohammad S Khuroo, Ajaz A Rather, Naira S Khuroo and Mehnaaz S Khuroo
Funding Agency and Grant Number	Funding Agency Grant Number Dr. Khuroo’s Medical Trust, a nonprofit organization which supports academic activities, disseminates medical education and helps poor patients for medical treatment
Corresponding Author	Mohammad S Khuroo, Director, Digestive Diseases Centre, Dr. Khuroo’s Medical Clinic, Sector 1, SK Colony, Qamarwari, Srinagar, Kashmir 190010, India. khuroo@yahoo.com
Key Words	Biliary disease; Extrahepatic portal venous obstruction; Portal cavernoma; Bile duct strictures; Bile duct calculi
Core Tip	Extrahepatic portal vein obstruction is often encountered in children in India. It is caused by long standing thrombosis of portal vein and leads to cavernous transformation of the bridging venous collaterals. Cholangiographic abnormalities occur in majority of such patients, however, the entity stays asymptomatic in early stages. Biliopathy is a progressive disease and patients surviving to adulthood develop more severe biliary abnormalities and present with clinical disease. Now, portal biliopathy is an important clinical entity faced by hepatologists in India. Since the disease was described in early 90’s, there have been important developments in definition, pathogenesis, diagnostic modalities and therapeutic interventions of portal biliopathy.
Publish Date	2016-09-14 19:04
Citation	Khuroo MS, Rather AA, Khuroo NS, Khuroo MS. Portal biliopathy. World J Gastroenterol 2016; 22(35): 7973-7982
URL	http://www.wjgnet.com/1007-9327/full/v22/i35/7973.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i35.7973

Full Article (PDF)	WJG-22-7973.pdf
Full Article (Word)	WJG-22-7973.doc
Manuscript File	26049-Review.docx
Answering Reviewers	26049-Answering reviewers.pdf
Audio Core Tip	26049-Audio core tip.wav
Conflict-of-Interest Disclosure Form	26049-Conflict-of-interest statement.pdf
Copyright License Agreement	26049-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	26049-Language certificate.pdf
Peer-review Report	26049-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	26049-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	26049-Scientific misconduct check.pdf
Scientific Editor Work List	26049-Scientific editor work list.pdf