Publication Name	World Journal of Clinical Cases
Manuscript ID	2742
Country	United States

Received	2013-03-11 11:21
Peer-Review Started	2013-03-11 11:55
To Make the First Decision	2013-03-25 15:09
Return for Revision	2013-04-01 17:23
Revised	2013-04-09 09:23
Second Decision	2013-05-18 16:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-05-19 23:32
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-06-25 10:17
Publish the Manuscript Online	2013-08-07 10:29

ISSN	2307-8960 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Urology & Nephrology
Manuscript Type	Case Report
Article Title	Desmopression is an effective adjunct treatment for reversing excessive hyponatremia overcorrection
Manuscript Source	Invited Manuscript
All Author List	Kamel A Gharaibeh, Matthew J Craig, Christian A Koch, Anna A Lerant, Tibor Fülöp and Éva Csongrádi
Funding Agency and Grant Number
Corresponding Author	Kamel A Gharaibeh, MD, Department of Internal Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216-4505, United States. kgharaibeh@umc.edu
Key Words	Hyponatremia; Hypokalemia; Overcorrection; Polyuria; Antidiuretic hormone; Vasopressin; Desmopressin; Osmotic demyelination syndrome; Central pontine myelinolysis
Core Tip	In euvolemic hyponatremic patients, controlling the underlying reason of excessive vasopressin secretion may lead to sudden, large-volume free water diuresis and rise of serum sodium exceeding 10 mmol/L per day. Polyuria after presentation with symptomatic hyponatremia is a serious warning sign and should not be ignored. These patients need frequent electrolyte monitoring and, in case of excessive rise of serum sodium, pure water replacement with 5% dextrose in water to achieve a targeted reduction in serum sodium levels. Early addition of an antidiuretic hormone analog, such as desmopressin, can limit urine output and improve patient outcome.
Publish Date	2013-08-07 10:29
Citation	Gharaibeh KA, Craig MJ, Koch CA, Lerant AA, Fül?p T, Csongrádi é. Desmopression is an effective adjunct treatment for reversing excessive hyponatremia overcorrection. World J Clin Cases 2013; 1(5): 155-158
URL	http://www.wjgnet.com/2307-8960/full/v1/i5/155.htm
DOI	http://dx.doi.org/10.12998/wjcc.v1.i5.155

Full Article (PDF)	WJCC-1-155.pdf
Manuscript File	2742-Review.docx
Answering Reviewers	2742-Answering reviewers.doc
Copyright License Agreement	2742-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Letter from IRB.pdf
Peer-review Report	2742-Peer review(s).pdf
Scientific Editor Work List	2742-Scientific editor work list.doc