Publication Name	World Journal of Biological Chemistry
Manuscript ID	29874
Country	India

Received	2016-08-30 09:22
Peer-Review Started	2016-09-01 10:04
To Make the First Decision	2016-09-26 08:50
Return for Revision	2016-09-29 11:54
Revised	2016-10-13 00:17
Second Decision	2016-12-06 10:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-12-14 17:23
Articles in Press	2016-12-14 17:23
Publication Fee Transferred
Edit the Manuscript by Language Editor	2016-12-21 15:21
Typeset the Manuscript	2017-02-20 08:45
Publish the Manuscript Online	2017-02-25 15:11

ISSN	1949-8454 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Neurosciences
Manuscript Type	Review
Article Title	Biochemical changes in the injured brain
Manuscript Source	Invited Manuscript
All Author List	Seelora Sahu, Deb Sanjay Nag, Amlan Swain and Devi Prasad Samaddar
Funding Agency and Grant Number
Corresponding Author	Dr. Deb Sanjay Nag, Department of Anaesthesia and Critical Care, Tata Main Hospital, C Road West, Northern Town, Bistupur, Jamshedpur 831011, India. debsanjay@gmail.com
Key Words	Biomarkers; Brain injuries; Brain ischemia; Epilepsy; Subarachnoid hemorrhage
Core Tip	The biochemical markers of brain injury are being increasingly used to assess the severity and prognosis in the injured brain. While S-100, glial fibrillary acidic protein and ubiquitin C terminal hydrolase have been used as early biomarkers to aid in clinical decision-making and initial management, other biomarkers help in long-term prognosis. Cerebral microdialysis is a novel way of monitoring brain tissue biochemical metabolites and each component gives an idea about the severity and type of pathologic process in the brain. In addition, small non-coding RNAs have presented themselves as potential markers of brain injury for future research.
Publish Date	2017-02-25 15:11
Citation	Sahu S, Nag DS, Swain A, Samaddar DP. Biochemical changes in the injured brain. World J Biol Chem 2017; 8(1): 21-31
URL	http://www.wjgnet.com/1949-8454/full/v8/i1/21.htm
DOI	http://dx.doi.org/10.4331/wjbc.v8.i1.21

Full Article (PDF)	WJBC-8-21.pdf
Full Article (Word)	WJBC-8-21.doc
Manuscript File	29874-Review.docx
Answering Reviewers	29874-Answering reviewers.pdf
Audio Core Tip	29874-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	29874-Conflict-of-interest statement.pdf
Copyright License Agreement	29874-Copyright assignment.pdf
Peer-review Report	29874-Peer-review(s).pdf
Scientific Misconduct Check	29874-Scientific misconduct check.pdf
Scientific Editor Work List	29874-Scientific editor work list.pdf