Publication Name	World Journal of Stem Cells
Manuscript ID	32946
Country	Japan

Received	2017-01-30 16:56
Peer-Review Started	2017-02-02 22:20
To Make the First Decision	2017-03-27 12:06
Return for Revision	2017-03-31 14:22
Revised	2017-04-27 13:17
Second Decision	2017-05-27 09:50
Accepted by Journal Editor-in-Chief	2017-05-28 06:48
Accepted by Company Editor-in-Chief	2017-06-08 01:32
Articles in Press	2017-06-08 01:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-11 00:55
Publish the Manuscript Online	2017-07-17 07:13

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Orthopedics
Manuscript Type	Basic Study
Article Title	Modifying oxygen tension affects bone marrow stromal cell osteogenesis for regenerative medicine
Manuscript Source	Invited Manuscript
All Author List	Yusuke Inagaki, Manabu Akahane, Takamasa Shimizu, Kazuya Inoue, Takuya Egawa, Tsutomu Kira, Munehiro Ogawa, Kenji Kawate and Yasuhito Tanaka
Funding Agency and Grant Number
Corresponding Author	Yusuke Inagaki, MD, PhD, Assistant Professor, Department of Orthopedic Surgery, Nara Medical University, 840 Shijo-cho, Kashihara Nara 634-8522, Japan. yinagaki@naramed-u.ac.jp
Key Words	Hypoxia; Osteogenesis; Tissue engineering; Marrow stromal cells; Regenerative medicine
Core Tip	Bone tissue engineering using marrow stromal cells (MSCs) is a promising method in regenerative medicine. Here, we have reported a scaffold-free transplantation technique using hypoxic-preconditioned osteogenic matrix cell sheets (OMCSs) derived from MSCs. We show that modifying the oxygen tension before implantation of OMCS composites led to an increased osteogenic capacity of rat bone MSCs.
Publish Date	2017-07-17 07:13
Citation	Inagaki Y, Akahane M, Shimizu T, Inoue K, Egawa T, Kira T, Ogawa M, Kawate K, Tanaka Y. Modifying oxygen tension affects bone marrow stromal cell osteogenesis for regenerative medicine. World J Stem Cells 2017; 9(7): 98-106
URL	http://www.wjgnet.com/1948-0210/full/v9/i7/98.htm
DOI	http://dx.doi.org/10.4252/wjsc.v9.i7.98

Full Article (PDF)	WJSC-9-98.pdf
Full Article (Word)	WJSC-9-98.doc
Manuscript File	32946-Review.docx
Answering Reviewers	32946-Answering reviewers.pdf
Audio Core Tip	32946-Audio core tip.mp3
Biostatistics Review Certificate	32946_9 32946-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	32946-Conflict-of-interest statement.pdf
Copyright License Agreement	32946-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	32946-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	32946-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	32946-Language certificate.pdf
Peer-review Report	32946-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	32946-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	32946-Scientific misconduct check.pdf
Scientific Editor Work List	32946-Scientific editor work list.pdf