BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/14/2017 4:00:08 AM | Browse: 1052 | Download: 1832
 |
Received |
|
2017-04-07 15:04 |
|
Peer-Review Started |
|
2017-04-10 11:55 |
 |
First Decision by Editorial Office Director |
|
|
|
Return for Revision |
|
2017-06-13 03:27 |
|
Revised |
|
2017-06-26 13:28 |
|
Publication Fee Transferred |
|
2017-07-13 12:44 |
|
Second Decision by Editor |
|
2017-07-11 05:42 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2017-07-12 07:00 |
|
Articles in Press |
|
2017-07-12 07:00 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2017-08-03 07:03 |
|
Publish the Manuscript Online |
|
2017-08-14 04:00 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Expression of Interleukin-26 is upregulated in inflammatory bowel disease
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Makoto Fujii, Atsushi Nishida, Hirotsugu Imaeda, Masashi Ohno, Kyohei Nishino, Shigeki Sakai, Osamu Inatomi, Shigeki Bamba, Masahiro Kawahara, Tomoharu Shimizu and Akira Andoh |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Atsushi Nishida, MD, PhD, Department of Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu 520-2192, Japan. atsuda@belle.shiga-med.ac.jp |
| Key Words |
Inflammatory bowel disease; Interleukin-26; Myofibroblasts |
| Core Tip |
We investigated interleukin (IL)-26 expression in the inflamed mucosa of patients with inflammatory bowel disease (IBD) and characterized the biological function of IL-26 using human colonic subepithelial myofibroblasts. To our knowledge, this is the first report to state that IL-26 activates STAT1/3 and leads to the induction of IL-6 and IL-8 expression in non-transformed cells derived from human colon. We suggest that IL-26 plays a role in the pathophysiology of IBD through the induction of inflammatory mediators. |
| Publish Date |
2017-08-14 04:00 |
| Citation |
Fujii M, Nishida A, Imaeda H, Ohno M, Nishino K, Sakai S, Inatomi O, Bamba S, Kawahara M, Shimizu T, Andoh A. Expression of Interleukin-26 is upregulated in inflammatory bowel disease. World J Gastroenterol 2017; 23(30): 5519-5529 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i30/5519.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i30.5519 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
