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8/14/2017 4:00:08 AM | Browse: 808 | Download: 1076
Publication Name World Journal of Gastroenterology
Manuscript ID 34197
Country Japan
Received
2017-04-07 15:04
Peer-Review Started
2017-04-10 11:55
To Make the First Decision
2017-06-08 00:29
Return for Revision
2017-06-13 03:27
Revised
2017-06-26 13:28
Second Decision
2017-07-11 05:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-07-12 07:00
Articles in Press
2017-07-12 07:00
Publication Fee Transferred
2017-07-13 12:44
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-08-03 07:03
Publish the Manuscript Online
2017-08-14 04:00
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Expression of Interleukin-26 is upregulated in inflammatory bowel disease
Manuscript Source Unsolicited Manuscript
All Author List Makoto Fujii, Atsushi Nishida, Hirotsugu Imaeda, Masashi Ohno, Kyohei Nishino, Shigeki Sakai, Osamu Inatomi, Shigeki Bamba, Masahiro Kawahara, Tomoharu Shimizu and Akira Andoh
ORCID
Author(s) ORCID Number
Makoto Fujii http://orcid.org/0000000313866260
Atsushi Nishida http://orcid.org/0000000212883272
Hirotsugu Imaeda http://orcid.org/0000000255168527
Masashi Ohno http://orcid.org/0000000335057835
Kyohei Nishino http://orcid.org/0000000197986731
Shigeki Sakai http://orcid.org/0000000218030617
Osamu Inatomi http://orcid.org/0000000258376575
Shigeki Bamba http://orcid.org/0000000241085894
Masahiro Kawahara http://orcid.org/0000000227217571
Tomoharu Shimizu http://orcid.org/0000000228580786
Akira Andoh http://orcid.org/0000000185332669
Funding Agency and Grant Number
Corresponding Author Atsushi Nishida, MD, PhD, Department of Medicine, Shiga University of Medical Science, Seta Tsukinowa, Otsu 520-2192, Japan. atsuda@belle.shiga-med.ac.jp
Key Words Inflammatory bowel disease; Interleukin-26; Myofibroblasts
Core Tip We investigated interleukin (IL)-26 expression in the inflamed mucosa of patients with inflammatory bowel disease (IBD) and characterized the biological function of IL-26 using human colonic subepithelial myofibroblasts. To our knowledge, this is the first report to state that IL-26 activates STAT1/3 and leads to the induction of IL-6 and IL-8 expression in non-transformed cells derived from human colon. We suggest that IL-26 plays a role in the pathophysiology of IBD through the induction of inflammatory mediators.
Publish Date 2017-08-14 04:00
Citation Fujii M, Nishida A, Imaeda H, Ohno M, Nishino K, Sakai S, Inatomi O, Bamba S, Kawahara M, Shimizu T, Andoh A. Expression of Interleukin-26 is upregulated in inflammatory bowel disease. World J Gastroenterol 2017; 23(30): 5519-5529
URL http://www.wjgnet.com/1007-9327/full/v23/i30/5519.htm
DOI http://dx.doi.org/10.3748/wjg.v23.i30.5519
Full Article (PDF) WJG-23-5519.pdf
Full Article (Word) WJG-23-5519.doc
Manuscript File 34197-Review.docx
Answering Reviewers 34197-Answering reviewers.pdf
Audio Core Tip 34197-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 34197-Conflict-of-Interest statement.pdf
Copyright License Agreement 34197-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 34197-Institutional review board statement.pdf
Supplementary Material 34197-Supplementary-Material-revision_2741.docx
Peer-review Report 34197-Peer-review(s).pdf
Scientific Misconduct Check 34197-Scientific misconduct check.pdf
Scientific Editor Work List 34197-Scientific editor work list.pdf