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Articles Published Processes
9/7/2017 8:51:55 AM | Browse: 1510 | Download: 2355
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Received |
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2017-05-04 10:06 |
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Peer-Review Started |
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2017-05-04 21:48 |
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To Make the First Decision |
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2017-06-05 00:58 |
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Return for Revision |
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2017-06-07 00:08 |
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Revised |
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2017-06-09 08:37 |
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Second Decision |
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2017-07-05 23:54 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-07-12 06:23 |
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Articles in Press |
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2017-07-12 06:23 |
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Publication Fee Transferred |
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2017-07-14 03:14 |
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Edit the Manuscript by Language Editor |
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2017-08-03 13:13 |
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Typeset the Manuscript |
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2017-08-25 06:13 |
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Publish the Manuscript Online |
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2017-09-07 08:51 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Retrospective Study |
| Article Title |
Ketogenic diet poses a significant effect on imbalanced gut microbiota in infants with refractory epilepsy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Gan Xie, Qian Zhou, Chuang-Zhao Qiu, Wen-Kui Dai, He-Ping Wang, Yin-Hu Li, Jian-Xiang Liao, Xin-Guo Lu, Su-Fang Lin, Jing-Hua Ye, Zhuo-Ya Ma and Wen-Jian Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shenzhen Science and Technology Innovation Committee |
JCYJ20150403100317071 |
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| Corresponding Author |
Wen-Jian Wang, Doctor, Doctor, Director for Department of Respiratory, Shenzhen Children’s Hospital, No.7019 Yitian Road, Shenzhen 518026, Guangdong Province, China. dhbk2005@163.com |
| Key Words |
Ketogenic diet; Cronobacter; Seizures; Gut microbiota; Epilepsy |
| Core Tip |
Many infants with epilepsy are refractory to current antiepileptic drugs, and ketogenic diet (KD) could help to moderate seizure frequency as an alternative treatment. A large number of reports have demonstrated that gut microbiota (GM) can affect children’s neurodevelopment. Concurrently, GM could be dramatically affected by diet. KD could rapidly alter GM and alleviate seizure frequency in infants with refractory epilepsy. The GM structure of epileptic infants - comprising large numbers of pathogens, such as Streptococcus - differed from that of healthy controls. After KD therapy, GM of epileptic patients changed significantly, with fewer pathogens and more beneficial bacteria. |
| Publish Date |
2017-09-07 08:51 |
| Citation |
Xie G, Zhou Q, Qiu CZ, Dai WK, Wang HP, Li YH, Liao JX, Lu XG, Lin SF, Ye JH, Ma ZY, Wang WJ. Ketogenic diet poses a significant effect on imbalanced gut microbiota in infants with refractory epilepsy. World J Gastroenterol 2017; 23(33): 6164-6171 |
| URL |
http://www.wjgnet.com/1007-9327/full/v23/i33/6164.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v23.i33.6164 |
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