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Articles Published Processes
10/16/2017 3:37:15 AM | Browse: 1201 | Download: 2879
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Received |
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2017-05-26 00:57 |
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Peer-Review Started |
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2017-05-27 00:13 |
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To Make the First Decision |
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2017-07-10 00:33 |
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Return for Revision |
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2017-07-11 02:44 |
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Revised |
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2017-07-21 15:35 |
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Second Decision |
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2017-08-10 03:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-09-05 01:47 |
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Articles in Press |
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2017-09-05 01:47 |
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Publication Fee Transferred |
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2017-09-07 19:27 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-10-13 03:27 |
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Publish the Manuscript Online |
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2017-10-16 03:37 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Herbal Traditional Chinese Medicine and suspected liver injury: A prospective study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dieter Melchart, Stefan Hager, Sabine Albrecht, Jingzhang Dai, Wolfgang Weidenhammer and Rolf Teschke |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dieter Melchart, MD, Competence Centre for Complementary Medicine and Naturopathy (CoCoNat), University Hospital Munich rechts der Isar, Technical University of Munich, Kaiserstrasse 9, Munich D-80801, Germany. dieter.melchart@tum.de |
| Key Words |
Traditional Chinese Medicine; Herbal medicine; Liver injury; Roussel Uclaf Causality Assessment Method; Herb induced liver injury |
| Core Tip |
Worldwide research on herbal medicine safety is still limited. Adverse effects are range from clinically not relevant to more severe ones including suspected liver injury. We conducted a prospective hospital-based study to report the number of new liver injury in patients with no liver disease prior to treatment with herbal Traditional Chinese Medicine. Liver injury was detected in 26/21470 patients (0.12%) with alanine aminotransferase values of ≥ 5 × upper limit normal. The Roussel Uclaf Causality Assessment Method assessed the causality of suspected cases and showed a causality level of “possible” for the majority of the liver injury cases. |
| Publish Date |
2017-10-16 03:37 |
| Citation |
Melchart D, Hager S, Albrecht S, Dai J, Weidenhammer W, Teschke R. Herbal Traditional Chinese Medicine and suspected liver injury: A prospective study. World J Hepatol 2017; 9(29): 1141-1157 |
| URL |
http://www.wjgnet.com/1948-5182/full/v9/i29/1141.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v9.i29.1141 |
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