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12/26/2017 1:51:01 AM | Browse: 1131 | Download: 819
Publication Name World Journal of Stem Cells
Manuscript ID 35835
Country/Territory Romania
Received
2017-08-26 05:52
Peer-Review Started
2017-08-26 12:18
To Make the First Decision
2017-10-23 00:29
Return for Revision
2017-10-24 03:53
Revised
2017-10-30 16:01
Second Decision
2017-11-20 02:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-11-28 02:05
Articles in Press
2017-11-28 02:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-12-19 08:35
Publish the Manuscript Online
2017-12-26 01:51
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Pursuing meaningful end-points for stem cell therapy assessment in ischemic cardiac disease
Manuscript Source Invited Manuscript
All Author List Maria Dorobantu, Nicoleta-Monica Popa-Fotea, Mihaela Popa, Iulia Rusu and Miruna Mihaela Micheu
ORCID
Author(s) ORCID Number
Maria Dorobantu http://orcid.org/0000-0002-1273-7056
Nicoleta-Monica Popa-Fotea http://orcid.org/0000-0002-8066-5779
Mihaela Popa http://orcid.org/0000-0003-4859-199X
Iulia Rusu http://orcid.org/0000-0001-9116-6484
Miruna Mihaela Micheu http://orcid.org/0000-0001-7201-3132
Funding Agency and Grant Number
Corresponding Author Miruna Mihaela Micheu, MD, PhD, Department of Cardiology, Clinical Emergency Hospital of Bucharest, Floreasca Street 8, Bucharest 014461, Romania. cardio@urgentafloreasca.ro
Key Words Stem cell therapy; Cardiac imaging techniques; Ischemic cardiac disease; Cardiac regeneration; End-points
Core Tip Although multiple studies have been published on stem cell therapy (SCT) in ischemic cardiac disease, no universal conclusion regarding its clinical efficacy has been given in part due to the lack of appropriate end-points. A rightful appreciation of SCT impact should be made considering multiple parameters from diverse categories, either objective - evaluating structural and biological functions, or subjective - patient orientated impacting daily quality of life. Current end-points, but also novel parameters investigating molecular pathways and new imaging methods with labelled cells genetically modified are being analytically discussed in this review, disclosing high heterogeneity in SCT efficacy assessment.
Publish Date 2017-12-26 01:51
Citation Dorobantu M, Popa-Fotea NM, Popa M, Rusu I, Micheu MM. Pursuing meaningful end-points for stem cell therapy assessment in ischemic cardiac disease. World J Stem Cells 2017; 9(12): 203-218
URL http://www.wjgnet.com/1948-0210/full/v9/i12/203.htm
DOI http://dx.doi.org/10.4252/wjsc.v9.i12.203
Full Article (PDF) WJSC-9-203.pdf
Full Article (Word) WJSC-9-203.doc
Manuscript File 35835-Review.docx
Answering Reviewers 35835-Answering reviewers.pdf
Audio Core Tip 35835-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 35835-Conflict-of-interest statement.pdf
Copyright License Agreement 35835-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 35835-Language certificate.pdf
Peer-review Report 35835-Peer-review(s).pdf
Scientific Misconduct Check 35835-Scientific misconduct check.pdf
Scientific Editor Work List 35835-Scientific editor work list.pdf