BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
1/7/2018 4:21:05 AM | Browse: 1176 | Download: 2463
 |
Received |
|
2017-09-01 00:26 |
|
Peer-Review Started |
|
2017-09-03 08:00 |
|
First Decision by Editorial Office Director |
|
2017-09-26 22:38 |
|
Return for Revision |
|
2017-09-28 08:46 |
|
Revised |
|
2017-11-23 02:17 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2017-11-27 10:45 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2017-11-27 20:33 |
|
Articles in Press |
|
2017-11-27 20:33 |
|
Edit the Manuscript by Language Editor |
|
2017-11-30 13:52 |
|
Typeset the Manuscript |
|
2018-01-05 00:56 |
|
Publish the Manuscript Online |
|
2018-01-07 04:21 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Emodin and baicalein inhibit sodium taurocholate-induced vacuole formation in pancreatic acinar cells
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun Li, Rui Zhou, Bei-Bei Bie, Na Huang, Ying Guo, Hai-Yan Chen, Meng-Jiao Shi, Jun Yang, Jian zhang and Zong-Fang Li |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
30901945 |
| Science Research Foundation of Shaanxi Administration of Traditional Chinese Medicine |
15-ZY029 |
| Science Research Foundation of the Second Affiliated Hospital of Xi’an Jiaotong University |
RC(XM)201602 |
|
| Corresponding Author |
Zong-Fang Li, MD, PhD, Chief Doctor, Professor, National & Local Joint Engineering Research Center of Biodiagnostics and Biotherapy, the Second Affiliated Hospital of Xi’an Jiaotong University, 157 West 5th Road, Xi’an 710004, Shaanxi Province, China. lzf2568@xjtu.edu.cn |
| Key Words |
inositol (1,4,5)-trisphosphate receptor; Severe acute pancreatitis; Calcium overload; Emodin; Baicalein; Pancreatic acinar cell |
| Core Tip |
combined use of emodin and baicalein (CEB) was found to act on key aspects of severe acute pancreatitis (SAP) pathogenesis; it regulated inflammatory factors and inhibited calcium overload, which underlie this synergy. These results at the cellular and organism levels reflect a preliminary mechanism of CEB in SAP and indicate that the development of CEB is promising for the treatment of patients with SAP. |
| Publish Date |
2018-01-07 04:21 |
| Citation |
Li J, Zhou R, Bie BB, Huang N, Guo Y, Chen HY, Shi MJ, Yang J, Zhang J, Li ZF. Emodin and baicalein inhibit sodium taurocholate-induced vacuole formation in pancreatic acinar cells. World J Gastroenterol 2018; 24(1): 35-45 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i1/35.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i1.35 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
