Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	37630
Country	France

Received	2017-12-22 15:12
Peer-Review Started	2017-12-22 19:35
To Make the First Decision	2018-01-05 01:13
Return for Revision	2018-01-06 04:23
Revised	2018-02-28 11:35
Second Decision	2018-03-02 04:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-03-06 23:55
Articles in Press	2018-03-06 23:55
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-03-24 19:07
Typeset the Manuscript	2018-04-09 14:27
Publish the Manuscript Online	2018-04-16 09:47

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Case Report
Article Title	EGFR amplification induces sensitivity to antiEGFR therapy in pancreatic acinar cell carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Corentin Richard, Julie Niogret, Romain Boidot and Francois Ghiringhelli
ORCID	Author(s) ORCID Number Corentin Richard http://orcid.org/0000-0001-9732-0219 Julie Niogret http://orcid.org/0000-0002-3563-4658 Romain Boidot http://orcid.org/0000-0001-9956-1737 Francois Ghiringhelli http://orcid.org/0000-0002-5465-8305
Funding Agency and Grant Number
Corresponding Author	Francois Ghiringhelli, MD, Professor, Department of Medical Oncology, Georges Francois Leclerc Cancer Center, 1 Rue Pr Marion, Dijon 21000, France. fghiringhelli@cgfl.fr
Key Words	Pancreatic cancer; Acinar cell carcinoma; Exome; Genetic mutations; Precision medicine
Core Tip	The role of genetic profiling for therapy of rare cancer for precision medicine is currently under investigation. This case report reports for the first time, that pancreatic acinar cell carcinoma could benefit from precision medicine and that EGFR gene amplification could be targetable by antiEGFR mAb in this pathology.
Publish Date	2018-04-16 09:47
Citation	Richard C, Niogret J, Boidot R, Ghiringhelli F. EGFR amplification induces sensitivity to antiEGFR therapy in pancreatic acinar cell carcinoma. World J Gastrointest Oncol 2018; 10(4): 103-107
URL	http://www. wjgnet.com/1948-5204/full/v10/i4/103.htm
DOI	http://dx.doi. org/10.4251/wjgo.v10.i4.103

Full Article (PDF)	WJGO-10-103.pdf
Full Article (Word)	WJGO-10-103.doc
CARE Checklist–2016	37630-CARE-checklist-(2013).pdf
Manuscript File	37630-Review.docx
Answering Reviewers	37630-Answering reviewers.pdf
Audio Core Tip	37630-Audio core tip.wma
Conflict-of-Interest Disclosure Form	37630-Conflict-of-interest statement.pdf
Copyright License Agreement	37630-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	37630-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	37630-Language certificate.pdf
Peer-review Report	37630-Peer-review(s).pdf
Scientific Misconduct Check	37630-Scientific misconduct check.pdf
Scientific Editor Work List	37630-Scientific editor work list.pdf