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Articles Published Processes
3/23/2018 1:28:41 PM | Browse: 1072 | Download: 1175
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Received |
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2018-02-19 14:39 |
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Peer-Review Started |
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2018-02-19 17:38 |
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To Make the First Decision |
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2018-03-13 00:12 |
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Return for Revision |
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2018-03-13 03:00 |
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Revised |
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2018-03-20 13:17 |
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Second Decision |
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2018-03-21 08:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-03-21 17:41 |
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Articles in Press |
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2018-03-21 17:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-03-22 11:12 |
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Publish the Manuscript Online |
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2018-03-23 13:28 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cell Biology |
Manuscript Type |
Review |
Article Title |
Physiologically based microenvironment for in vitro neural differentiation of adipose-derived stem cells
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Manuscript Source |
Invited Manuscript |
All Author List |
Adriana Carol Eleonora Graziano, Rosanna Avola, Vincenzo Perciavalle, Ferdinando Nicoletti, Gianluca Cicala, Marinella Coco and Venera Cardile |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
university of Catania - FIR2014 |
21040104 |
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Corresponding Author |
Adriana Carol Eleonora Graziano, PharmD, PhD, Research Fellow, Department of Biomedical and Biotechnological Sciences, Section of Physiology, University of Catania, Via Santa Sofia 97, Catania 95123, Italy. acegraz@unict.it |
Key Words |
Adipose stem cells; Biomaterials; Neurodegeneration; Neural differentiation; Physiological microenvironment |
Core Tip |
Adipose-derived stem cells are easily accessible from liposuction, obtained in large quantity and cultured for several months with low levels of senescence. Moreover, they could be induced toward a neural phenotype in vitro. The preclinical studies show that microenvironment has a predominant role. Our objective is to consolidate the current literature to better delineate the functional response of adipose-derived stem cells to biochemical, biophysical or dimensional stimuli. Specifically, chemicals - like drugs and growth factors-biomaterials and microgravity are here discussed as both single and co-applied parameters for inducing a neural lineage. |
Publish Date |
2018-03-23 13:28 |
Citation |
Graziano ACE, Avola R, Perciavalle V, Nicoletti F, Cicala G, Coco M, Cardile V. Physiologically based microenvironment for in vitro neural differentiation of adipose-derived stem cells. World J Stem Cells 2018; 10(3): 23-33 |
URL |
http://www.wjgnet.com/1948-0210/full/v10/i3/23.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v10.i3.23 |
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