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Articles Published Processes
9/15/2018 11:10:20 AM | Browse: 1050 | Download: 1784
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Received |
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2018-03-27 06:45 |
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Peer-Review Started |
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2018-03-27 11:52 |
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To Make the First Decision |
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2018-04-16 06:42 |
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Return for Revision |
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2018-04-18 07:58 |
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Revised |
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2018-06-13 21:56 |
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Second Decision |
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2018-06-26 12:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-06-27 23:12 |
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Articles in Press |
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2018-06-27 23:12 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-09-12 11:18 |
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Publish the Manuscript Online |
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2018-09-15 11:10 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Review |
Article Title |
Priming the seed: Helicobacter pylori alters epithelial cell invasiveness in early gastric carcinogenesis
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Manuscript Source |
Invited Manuscript |
All Author List |
Silvia Molina-Castro, Vanessa Ramírez-Mayorga and Warner Alpízar-Alpízar |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Vicerrectoría de Investigación of the University of Costa Rica |
B6A11 |
Vicerrectoría de Investigación of the University of Costa Rica |
B7281 |
Vicerrectoría de Investigación of the University of Costa Rica |
90912 |
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Corresponding Author |
Warner Alpízar-Alpízar, PhD, Professor, Centro de Investigación en Estructuras Microscópicas, Universidad de Costa Rica, San José 2060, Costa Rica. warner.alpizar@ucr.ac.cr |
Key Words |
Helicobacter pylori; Plasminogen activation system; Invasion; Epithelial-to-mesenchymal transition; Cell polarity; Gastric carcinogenesis |
Core Tip |
Helicobacter pylori (H. pylori) infection induces chronic inflammation in the gastric mucosa that, in the absence of treatment, may progress through a series of steps to gastric cancer (GC). GC is only one of several clinical outcomes associated with this bacterial infection, which may be at least partially attributed to the high genetic variability of H. pylori. Accumulating evidence implicates H. pylori in the manipulation of cellular and molecular programs that are crucial for conferring the cells with invasive capabilities, including reprograming of the epithelial-to-mesenchymal transition signaling programs, changing of the cell apicobasal polarity, and remodeling of the extracellular matrix. |
Publish Date |
2018-09-15 11:10 |
Citation |
Molina-Castro S, Ramírez-Mayorga V, Alpízar-Alpízar W. Priming the seed: Helicobacter pylori alters epithelial cell invasiveness in early gastric carcinogenesis. World J Gastrointest Oncol 2018; 10(9): 231-243 |
URL |
http://www.wjgnet.com/1948-5204/full/v10/i9/231.htm |
DOI |
http://dx.doi.org/10.4251/wjgo.v10.i9.231 |
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