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Articles Published Processes
9/27/2018 9:38:46 AM | Browse: 1114 | Download: 1846
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Received |
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2018-04-06 06:38 |
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Peer-Review Started |
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2018-04-07 06:59 |
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To Make the First Decision |
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2018-05-09 00:25 |
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Return for Revision |
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2018-05-09 02:24 |
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Revised |
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2018-05-09 07:05 |
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Second Decision |
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2018-05-22 09:35 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-05-24 03:29 |
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Articles in Press |
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2018-05-24 03:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-07-30 06:18 |
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Publish the Manuscript Online |
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2018-09-27 09:38 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Tien S Dong, Elizabeth S Aby, Jihane N Benhammou, Jenna Kawamoto, Steven-Huy Han, Folasade P May and Joseph R Pisegna |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Tien S Dong, MD, Academic Fellow, the Vatche and Tamar Manoukian Division of Digestive Diseases, University of California Los Angeles, Department of Medicine, University of California David Geffen School of Medicine, 10945 Le Conte Ave, PVUB 2114 MC694907, Los Angeles, CA 90095, United States. tsdong@mednet.ucla.edu |
Key Words |
Hepatitis C virus; Hemoglobin A1c; Diabetes mellitus; Direct-acting antivirals; Metabolic syndrome |
Core Tip |
The relationship of chronic hepatitis C virus (HCV) and type 2 diabetes mellitus is complex and lesser is known about its relationship to metabolic syndrome. While metabolic syndrome and type 2 diabetes may have had negative outcomes during the era of pegylated-interferon, research is being actively pursued to understand how direct acting antivirals (DAA) may affect these comorbidities. In this study, we show that unlike with pegylated-interferon, direct active antiviral success rates are not affected by the presence of metabolic syndrome. We further show that successful treatment of HCV with DAAs actually leads to better glycemic control 1-year post-treatment. |
Publish Date |
2018-09-27 09:38 |
Citation |
Dong TS, Aby ES, Benhammou JN, Kawamoto J, Han SH, May FP, Pisegna JR. Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c. World J Hepatol 2018; 10(9): 612-621 |
URL |
http://www.wjgnet.com/1948-5182/full/v10/i9/612.htm |
DOI |
http://dx.doi.org/10.4254/wjh.v10.i9.612 |
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