Publication Name	World Journal of Diabetes
Manuscript ID	39672
Country	United States

Received	2018-05-02 00:48
Peer-Review Started	2018-05-03 23:56
To Make the First Decision	2018-06-08 02:57
Return for Revision	2018-06-08 07:18
Revised	2018-06-15 18:54
Second Decision	2018-06-26 12:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-06-28 03:40
Articles in Press	2018-06-28 03:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-10-09 02:57
Publish the Manuscript Online	2018-10-12 11:58

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Peripheral Vascular Disease
Manuscript Type	Systematic Reviews
Article Title	Topical application of platelet-rich plasma for diabetic foot ulcers: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Takashi Hirase, Eric Ruff, Iqbal Ratnani and Salim Surani
ORCID	Author(s) ORCID Number Takashi Hirase http://orcid.org/0000-0001-9111-0667 Eric Ruff http://orcid.org/0000-0002-5084-8865 Iqbal Ratnani http://orcid.org/0000-0002-1168-3041 Salim Surani http://orcid.org/0000-0001-7105-4266
Funding Agency and Grant Number
Corresponding Author	Salim Surani, FACC, FACP, MD, Adjunct Professor, Department of Medicine, Pulmonary, Critical Care and Sleep Medicine, Texas A and M University, 701 Ayers street, Corpus Christi, TX 78404, United States. srsurani@hotmail.com
Key Words	Platelet rich plasma; Diabetes; Foot; Ulcer; Wound
Core Tip	There is growing evidence supporting the use of autologous platelet-rich plasma (PRP) to enhance the healing process of diabetic foot ulcers (DFUs). This systematic review of eleven articles (322 PRP subjects, 126 controls) showed that healing rate was significantly faster with PRP application compared to controls (0.68 ± 0.56 cm2/wk vs 0.39 ± 0.09 cm2/wk; p < 0.001). There were significantly lower adverse effects reported with PRP application compared to controls. The authors conclude that the topical application of PRP for DFUs results in statistically superior healing rates compared to controls with lower complication rates.
Publish Date	2018-10-12 11:58
Citation	Hirase T, Ruff E, Surani S, Ratnani I. Topical application of platelet-rich plasma for diabetic foot ulcers: A systematic review. World J Diabetes 2018; 9(10): 172-179
URL	http://www.wjgnet.com/1948-9358/full/v9/i10/172.htm
DOI	http://dx.doi.org/10.4239/wjd.v9.i10.172

Full Article (PDF)	WJD-9-172.pdf
Full Article (Word)	WJD-9-172.doc
PRISMA 2009 Checklist	39672-PRISMA 2009 checklist.pdf
Manuscript File	39672-Review.docx
Answering Reviewers	39672-Answering reviewers.pdf
Audio Core Tip	39672-Audio core tip.mp3
Biostatistics Review Certificate	39672-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	39672-Conflict-of-interest statement.pdf
Copyright License Agreement	39672-Copyright assignment.pdf
Supplementary Material	39672-Supplementary-Material-revision.docx
Peer-review Report	39672-Peer-review(s).pdf
Scientific Misconduct Check	39672-Scientific misconduct check.pdf
Scientific Editor Work List	39672-Scientific editor work list.pdf