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12/14/2018 3:36:55 AM | Browse: 650 | Download: 912
Publication Name World Journal of Transplantation
Manuscript ID 39927
Country Saudi Arabia
Received
2018-05-23 00:58
Peer-Review Started
2018-05-25 00:11
To Make the First Decision
2018-07-09 07:52
Return for Revision
2018-07-10 08:21
Revised
2018-09-07 07:34
Second Decision
2018-11-01 02:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-11-03 04:50
Articles in Press
2018-11-03 04:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-11-26 06:20
Publish the Manuscript Online
2018-12-14 03:36
ISSN 2220-3230 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Cohort Study
Article Title Graft vs host disease impacts overall survival post allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia/lymphoma
Manuscript Source Invited Manuscript
All Author List Moussab Damlaj, Mohammad Snnallah, Ayman Alhejazi, Samer Ghazi, Bader Alahmari, Ahmed Alaskar and Mohsen Alzahrani
ORCID
Author(s) ORCID Number
Moussab Damlaj http://orcid.org/0000-0001-8326-2193
Mohammad Snnallah http://orcid.org/0000-0001-8846-3584
Ayman Alhejazi http://orcid.org/0000-0002-2142-2654
Samer Ghazi http://orcid.org/0000-0003-2005-6530
Bader Alahmari http://orcid.org/0000-0002-6026-1347
Ahmed Alaskar http://orcid.org/0000-0002-0648-3256
Mohsen Alzahrani http://orcid.org/0000-0002-9174-5803
Funding Agency and Grant Number
Corresponding Author Moussab Damlaj, FACP, FRCP (C), MD, Assistant Professor, Doctor, Division of Hematology and HCT, Department of Oncology, King Abdulaziz Medical City, P.O. Box 22490, Riyadh 11426, Saudi Arabia. damlajmo@ngha.med.sa
Key Words Acute lymphoblastic leukemia; Allogeneic hematopoietic stem cell transplant; Lymphoblastic lymphoma; Complete remission
Core Tip Allogeneic hematopoietic stem cell transplantation (HCT) is a potentially curative therapy for acute lymphoblastic leukemia/lymphoma (ALL/LBL) patients. We examined the outcome and prognostic factors of HCT for high risk ALL/LBL at our center. After due institutional review board approval, 69 patients were enrolled. After a median follow up of 15 mo (2-87.3), the 2-year overall survival (OS) was 62.8%. In a multivariable analysis; B-cell subtype, first complete remission status, acute graft vs host disease (GVHD) and chronic GVHD predicted OS. In conclusion, allogeneic-HCT for ALL/LBL results in promising remissions in high risk disease and early referral for HCT to be considered for young and fit patients.
Publish Date 2018-12-14 03:36
Citation Damlaj M, Snnallah M, Alhejazi A, Ghazi S, Alahmari B, Alaskar A, Al-Zahrani M. Graft vs host disease impacts overall survival post allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia/lymphoma. World J Transplant 2018; 8(7): 252-258
URL http://www.wjgnet.com/2220-3230/full/v8/i7/252.htm
DOI http://dx.doi.org/10.5500/wjt.v8.i7.252
Full Article (PDF) WJT-8-252.pdf
Full Article (Word) WJT-8-252.doc
STROBE Statement 39927-STROBE statement.pdf
Manuscript File 39927-Review.docx
Answering Reviewers 39927-Answering reviewers.pdf
Audio Core Tip 39927-Audio core tip.mp3
Biostatistics Review Certificate 39927-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 39927-Conflict-of-interest statement.pdf
Copyright License Agreement 39927-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 39927-Approved-Grant-Application-Form(s)-or-Funding-Agency-Copy-of-any-Approval-Document(s)-revision.pdf
Signed Informed Consent Form(s) or Document(s) 39927-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 39927-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 39927-Language certificate.pdf
Video 39927-Video-revision.docx
Supplementary Material 39927-Supplementary-Material-revision.docx
Peer-review Report 39927-Peer-review(s).pdf
Scientific Misconduct Check 39927-Scientific misconduct check.pdf
Scientific Editor Work List 39927-Scientific editor work list.pdf