Publication Name	World Journal of Clinical Cases
Manuscript ID	40627
Country	China

Received	2018-07-02 00:39
Peer-Review Started	2018-07-02 01:55
First Decision by Editorial Office Director	2018-07-29 18:23
Return for Revision	2018-08-07 01:57
Revised	2018-08-21 15:09
Publication Fee Transferred
Second Decision by Editor	2018-08-28 10:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2018-08-28 14:32
Articles in Press	2018-08-28 14:32
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-10-18 07:01
Publish the Manuscript Online	2018-10-26 14:57

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Medicine, Research & Experimental
Manuscript Type	Case Report
Article Title	CNKSR2 mutation causes the X-linked epilepsy-aphasia syndrome: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Ying Sun, Yi-Dan Liu, Zhi-Feng Xu, Qing-Xia Kong and Yan-Ling Wang
ORCID	Author(s) ORCID Number Ying Sun http://orcid.org/0000-0001-5585-671X Yi-Dan Liu http://orcid.org/0000-0001-8470-4512 Zhi-Feng Xu http://orcid.org/0000-0002-3801-8666 Qing-Xia Kong http://orcid.org/0000-0003-3803-5789 Yan-Ling Wang http://orcid.org/0000-0002-3429-0208
Funding Agency and Grant Number	Funding Agency Grant Number Jining Medical University JYP201740
Corresponding Author	Qing-Xia Kong, MD, PhD, Chief Doctor, Department of Neurology, Affiliated Hospital of Jining Medical University, Guhuai Road No. 89, Jining 272000, Shandong Province, China. kxdqy8@sohu.com
Key Words	Epilepsy; Language impairment; Mental retardation; De novo mutation of CNKSR2; X-linked epilepsy-aphasia syndrome
Core Tip	Patient with epileptic seizures and progressive language impairment. Genetic testing revealed a de novo mutation of the CNKSR2 gene in the child and was not detected in the parents. Therefore, the gene may lead to X-linked epilepsy aphasia syndrome.
Publish Date	2018-10-26 14:57
Citation	Sun Y, Liu YD, Xu ZF, Kong QX, Wang YL. CNKSR2 mutation causes the X-linked epilepsy-aphasia syndrome: A case report and review of literature. World J Clin Cases 2018; 6(12): 570-576
URL	http://www.wjgnet.com/2307-8960/full/v6/i12/570.htm
DOI	http://dx.doi.org/10.12998/wjcc.v6.i12.570

Full Article (PDF)	WJCC-6-570.pdf
Full Article (Word)	WJCC-6-570.doc
CARE Checklist–2016	40627-CARE checklist (2013).pdf
Manuscript File	40627-Review.docx
Answering Reviewers	40627-Answering reviewers.pdf
Audio Core Tip	40627-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	40627-Conflict-of-interest statement.pdf
Copyright License Agreement	40627-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	40627-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	40627-Language certificate.pdf
Peer-review Report	40627-Peer-review(s).pdf
Scientific Misconduct Check	40627-Scientific misconduct check.pdf
Scientific Editor Work List	40627-Scientific editor work list.pdf