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Articles Published Processes
11/21/2018 4:08:59 AM | Browse: 829 | Download: 1756
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Received |
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2018-08-02 06:41 |
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Peer-Review Started |
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2018-08-02 06:57 |
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To Make the First Decision |
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2018-10-08 03:43 |
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Return for Revision |
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2018-10-08 07:24 |
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Revised |
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2018-10-17 08:58 |
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Second Decision |
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2018-10-19 09:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-10-21 06:39 |
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Articles in Press |
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2018-10-21 06:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-11-05 23:56 |
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Typeset the Manuscript |
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2018-11-15 00:58 |
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Publish the Manuscript Online |
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2018-11-21 04:08 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Prognostic value of sorting nexin 10 weak expression in stomach adenocarcinoma revealed by weighted gene co-expression network analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun Zhang, Yue Wu, Hao-Yi Jin, Shuai Guo, Zhe Dong, Zhi-Chao Zheng, Yue Wang and Yan Zhao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Liaoning S&T Project |
2015020269 |
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| Corresponding Author |
Yan Zhao, PhD, Professor, Department of Gastric Cancer, Liaoning Cancer Hospital and Institute (Cancer Hospital of China Medical University), No. 44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China. zhaoyan@cancerhosp-ln-cmu.com |
| Key Words |
Stomach adenocarcinoma; The Cancer Genome Atlas; Weighted gene co-expression network analysis; Sorting nexin 10; Clinicopathological predictors; Disease-free survival; Overall survival |
| Core Tip |
This study used The Cancer Genome Atlas (TCGA) and clinical data to identify sorting nexin (SNX)10 as associated with poor prognosis in stomach adenocarcinoma (SA). Firstly, we downloaded the TCGA-STAD RNA-seq data through R and identified the differentially expressed genes. Weighted gene co-expression network analysis was used to clarify the connection between modules and clinical information. We then chose SNX10 as the hub-gene of the tan-module after considering module membership, genes with high gene significance, degree and Molecular Complex Detection scores. Our center’s SA data were used to evaluate our hypothesis. Our findings demonstrated that weak expression of SNX10 is linked to poor SA prognosis. |
| Publish Date |
2018-11-21 04:08 |
| Citation |
Zhang J, Wu Y, Jin HY, Guo S, Dong Z, Zheng ZC, Wang Y, Zhao Y. Prognostic value of sorting nexin 10 weak expression in stomach adenocarcinoma revealed by weighted gene co-expression network analysis. World J Gastroenterol 2018; 24(43): 4906-4919 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i43/4906.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i43.4906 |
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