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11/26/2018 6:26:45 AM | Browse: 654 | Download: 633
Publication Name World Journal of Clinical Cases
Manuscript ID 41494
Country/Territory Japan
Received
2018-08-20 09:20
Peer-Review Started
2018-08-21 03:26
To Make the First Decision
2018-10-12 00:27
Return for Revision
2018-10-12 06:49
Revised
2018-10-21 01:49
Second Decision
2018-10-22 08:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-10-22 21:35
Articles in Press
2018-10-22 21:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-11-19 08:01
Publish the Manuscript Online
2018-11-26 06:26
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Case Report
Article Title Acquired hemophilia A in solid cancer: Two case reports and review of the literature
Manuscript Source Unsolicited Manuscript
All Author List Makoto Saito, Reiki Ogasawara, Koh Izumiyama, Akio Mori, Takeshi Kondo, Masanori Tanaka, Masanobu Morioka and Masahiro Ieko
ORCID
Author(s) ORCID Number
Makoto Saito http://orcid.org/0000-0002-2683-9475
Reiki Ogasawara http://orcid.org/0000-0002-1136-5035
Koh Izumiyama http://orcid.org/0000-0002-0762-6255
Akio Mori http://orcid.org/0000-0002-2064-2145
Takeshi Kondo http://orcid.org/0000-0001-7455-5824
Masanori Tanaka http://orcid.org/0000-0002-8173-6620
Masanobu Morioka http://orcid.org/0000-0002-0784-8114
Masahiro Ieko http://orcid.org/0000-0003-1854-4543
Funding Agency and Grant Number
Corresponding Author Makoto Saito, MD, PhD, Department of Internal Medicine and Hematology, Aiiku Hospital, Minami 4 Nishi 25 Chuo Ku, Sapporo 0640804, Hokkaido, Japan. ikyoku@aiiku-hp.or.jp
Key Words Acquired hemophilia A; Coagulation factor Ⅷ; Solid cancer; Gastric cancer; Hepatocellular carcinoma; Case report
Core Tip Acquired hemophilia A (AHA) is a rare he­morrhagic disease usually affecting the elderly, involving reduced coagulation factor Ⅷ activity. Malignancies are reported to occur in association with 10%-15% of patients with AHA. We report two cases of AHA in solid cancer, namely, gastric cancer and hepatocellular carcinoma. Hemostasis was fully achieved owing to eradication of inhibitor against factor Ⅷ, however, both patients died within 1 year due to cancer progression. Successful treatment for AHA in solid cancer can be difficult because not only active hemorrhage management and inhibitor eradica­tion but also treatment of the underlying malignancy is required.
Publish Date 2018-11-26 06:26
Citation Saito M, Ogasawara R, Izumiyama K, Mori A, Kondo T, Tanaka M, Morioka M, Ieko M. Acquired hemophilia A in solid cancer: Two case reports and review of the literature. World J Clin Cases 2018; 6(14): 781-785
URL http://www.wjgnet.com/2307-8960/full/v6/i14/781.htm
DOI http://dx.doi.org/10.12998/wjcc.v6.i14.781
Full Article (PDF) WJCC-6-781.pdf
Full Article (Word) WJCC-6-781.doc
CARE Checklist–2016 41494-CARE Checklist (2013).pdf
Manuscript File 41494-Review.docx
Answering Reviewers 41494-Answering reviewers.pdf
Audio Core Tip 41494-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 41494-Conflict-of-interest statement.pdf
Copyright License Agreement 41494-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 41494-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 41494-Language certificate.pdf
Peer-review Report 41494-Peer-review(s).pdf
Scientific Misconduct Check 41494-Scientific misconduct check.pdf
Scientific Editor Work List 41494-Scientific editor work list.pdf