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Articles Published Processes
2/15/2019 9:46:42 AM | Browse: 969 | Download: 925
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Received |
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2018-11-14 02:46 |
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Peer-Review Started |
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2018-11-15 00:33 |
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To Make the First Decision |
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2018-12-25 01:21 |
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Return for Revision |
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2018-12-28 07:08 |
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Revised |
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2018-12-31 20:54 |
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Second Decision |
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2019-01-22 10:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-01-28 19:10 |
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Articles in Press |
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2019-01-28 19:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-02-15 01:26 |
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Publish the Manuscript Online |
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2019-02-15 09:46 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Anal carcinoma in giant anal condyloma, multidisciplinary approach necessary for optimal outcome: Two case reports and review of literature
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Santosh Shenoy, Murali Nittala and Yazen Assaf |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Santosh Shenoy, MD, Surgeon, Surgical Oncologist, Department of General and Colorectal Surgery, KCVA and University of Missouri at Kansas City, 4801 E Linwood Blvd., Kansas city, MO 64128, United States. shenoy2009@hotmail.com |
| Key Words |
Squamous cell carcinoma of anus; Human papilloma virus infection; Giant anal condyloma; Buschke-Lowenstein tumor; Multidisciplinary treatment; Case report |
| Core Tip |
Large anal condylomas are generally caused by low risk human papilloma virus 6, 11, however in certain instances can be caused by high risk subtypes 16, 18, 31, 33. Malignant transformation to squamous cell carcinoma may occur in large neglected tumors and human immunodeficiency virus (HIV) patients. Deep core biopsy, P16 staining and positron emission tomography computed tomography scans are necessary to diagnose carcinoma and metastases. Due to enormous size of the tumors a multidisciplinary team approach is necessary with combination of neoadjuvant chemo radiation followed by wide excision of these tumors. Large perineal and pelvic defects may need pelvic reconstructive surgery. Patients with HIV and anal cancers carry a poor prognosis. |
| Publish Date |
2019-02-15 09:46 |
| Citation |
Shenoy S, Nittala M, Assaf Y. Anal carcinoma in giant anal condyloma, multidisciplinary approach necessary for optimal outcome: Two case reports and review of literature. World J Gastrointest Oncol 2019; 11(2): 172-180 |
| URL |
https://www.wjgnet.com/1948-5204/full/v11/i2/172.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v11.i2.172 |
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