Publication Name	World Journal of Anesthesiology
Manuscript ID	4420
Country	Taiwan

Received	2013-06-29 18:22
Peer-Review Started	2013-06-29 19:56
To Make the First Decision	2013-08-21 18:34
Return for Revision	2013-08-23 17:50
Revised	2013-09-20 16:38
Second Decision	2013-11-01 16:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-03 11:12
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-26 10:15
Publish the Manuscript Online	2014-03-11 12:20

ISSN	2218-6182 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Neurosciences
Manuscript Type	Review
Article Title	Molecular mechanism of inflammatory pain
Manuscript Source	Invited Manuscript
All Author List	Yeu-Shiuan Su, Wei-Hsin Sun and Chih-Cheng Chen
Funding Agency and Grant Number
Corresponding Author	Chih-Cheng Chen, PhD, Institute of Biomedical Sciences, Academia Sinica, 128 Academia Road, Section 2, Taipei 115, Taiwan. chih@ibms.sinica.edu.tw
Key Words	Acid-sensing ion channel; Acidosis; G-protein-coupled receptor; Inflammation; Proton-sensing ion channel; Transient receptor potential V1
Core Tip	Tissue acidosis that occurs during inflammation is central to the development and maintenance of chronic pain. Recent studies have revealed a variety of proton-sensing ion channels (e.g., acid-sensing ion channels, transient receptor potential V1) and G-protein-coupled receptors (e.g., G2 accumulation 2A, G-protein-coupled receptor 4, ovarian cancer G-protein-coupled receptor, T-cell death-associated gene 8) responsible for acid-induced pain. These cell-surface membrane proteins are promising therapeutic targets for the development of new analgesic drugs for chronic inflammatory pain.
Publish Date	2014-03-11 12:20
Citation	Su YS, Sun WH, Chen CC. Molecular mechanism of inflammatory pain. World J Anesthesiol 2014; 3(1): 71-81 Available from: URL: http://www.wjgnet.com/2218-6182/full/v3/i1/71.htm DOI: http://dx.doi.org/10.5313/wja.v3.i1.71
URL	http://www.wjgnet.com/2218-6182/full/v3/i1/71.htm
DOI	http://dx.doi.org/10.5313/wja.v3.i1.71

Full Article (PDF)	WJA-3-71.pdf
Full Article (Word)	WJA-3-71.doc
Manuscript File	4420-Review.docx
Answering Reviewers	4420-Answering reviewers.pdf
Copyright License Agreement	4420-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4420-Language certificate.pdf
Peer-review Report	4420-Peer review(s).pdf
Scientific Editor Work List	4420-Scientific editor work list.doc