Publication Name	World Journal of Stem Cells
Manuscript ID	46652
Country	Australia

Received	2019-02-22 02:13
Peer-Review Started	2019-02-24 01:35
To Make the First Decision	2019-06-05 06:46
Return for Revision	2019-06-06 03:51
Revised	2019-06-07 01:24
Second Decision	2019-06-18 03:03
Accepted by Journal Editor-in-Chief	2019-06-19 19:36
Accepted by Company Editor-in-Chief	2019-06-27 18:41
Articles in Press	2019-06-27 18:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-07-25 03:01
Publish the Manuscript Online	2019-07-26 00:39

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Minireviews
Article Title	Using transcription factors for direct reprogramming of neurons in vitro
Manuscript Source	Invited Manuscript
All Author List	Layal El Wazan, Daniel Urrutia-Cabrera and Raymond Ching-Bong Wong
ORCID	Author(s) ORCID Number Layal El Wazan http://orcid.org/0000-0002-9869-2951 Daniel Urrutia-Cabrera http://orcid.org/0000-0002-4610-5719 Raymond Ching-Bong Wong http://orcid.org/0000-0002-8092-9455
Funding Agency and Grant Number	Funding Agency Grant Number Ophthalmic Research Institute of Australia University of Melbourne the Kel and Rosie Day Foundation Centre for Eye Research Australia
Corresponding Author	Raymond Ching-Bong Wong, BSc, PhD, Adjunct Professor, Cellular Reprogramming Unit, Centre for Eye Research Australia, Level 6, 75 Commercial Road, Melbourne 3002, Australia. wongcb@unimelb.edu.au
Key Words	Cell reprogramming; Neuronal subtypes; Transcription factors; Direct reprogramming; Glutamatergic neurons; GABAergic neurons
Core Tip	Direct reprogramming represents an innovative technology to generate neurons in the lab, which can be used for cell therapy, drug screening and disease modeling for neurodegenerative diseases. In this review we will discuss the current advance in identifying transcription factors to promote direct reprogramming of specialized neuronal subtypes, including glutamatergic, GABAergic, dopaminergic, sensory and retinal neurons. We will also discuss the hurdles that need to be overcome for clinical translation.
Publish Date	2019-07-26 00:39
Citation	El Wazan L, Urrutia-Cabrera D, Wong RCB. Using transcription factors for direct reprogramming of neurons in vitro. World J Stem Cells 2019; 11(7): 431-444
URL	https://www.wjgnet.com/1948-0210/full/v11/i7/431.htm
DOI	https://dx.doi.org/10.4252/wjsc.v11.i7.431

Full Article (PDF)	WJSC-11-431.pdf
Full Article (Word)	WJSC-11-431.docx
Manuscript File	46652-Review.docx
Answering Reviewers	46652-Answering reviewers.pdf
Audio Core Tip	46652-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	46652-Conflict-of-interest statement.pdf
Copyright License Agreement	46652-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	46652-Grant application form(s).pdf
Peer-review Report	46652-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	46652-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	46652-Scientific misconduct check.pdf
Scientific Editor Work List	46652-Scientific editor work list.pdf