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Articles Published Processes
7/26/2019 12:39:36 AM | Browse: 641 | Download: 984
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Received |
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2019-02-22 02:13 |
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Peer-Review Started |
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2019-02-24 01:35 |
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To Make the First Decision |
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2019-06-05 06:46 |
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Return for Revision |
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2019-06-06 03:51 |
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Revised |
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2019-06-07 01:24 |
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Second Decision |
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2019-06-18 03:03 |
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Accepted by Journal Editor-in-Chief |
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2019-06-19 19:36 |
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Accepted by Executive Editor-in-Chief |
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2019-06-27 18:41 |
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Articles in Press |
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2019-06-27 18:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-07-25 03:01 |
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Publish the Manuscript Online |
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2019-07-26 00:39 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Using transcription factors for direct reprogramming of neurons in vitro
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Layal El Wazan, Daniel Urrutia-Cabrera and Raymond Ching-Bong Wong |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ophthalmic Research Institute of Australia |
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| University of Melbourne |
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| the Kel and Rosie Day Foundation |
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| Centre for Eye Research Australia |
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| Corresponding Author |
Raymond Ching-Bong Wong, BSc, PhD, Adjunct Professor, Cellular Reprogramming Unit, Centre for Eye Research Australia, Level 6, 75 Commercial Road, Melbourne 3002, Australia. wongcb@unimelb.edu.au |
| Key Words |
Cell reprogramming; Neuronal subtypes; Transcription factors; Direct reprogramming; Glutamatergic neurons; GABAergic neurons |
| Core Tip |
Direct reprogramming represents an innovative technology to generate neurons in the lab, which can be used for cell therapy, drug screening and disease modeling for neurodegenerative diseases. In this review we will discuss the current advance in identifying transcription factors to promote direct reprogramming of specialized neuronal subtypes, including glutamatergic, GABAergic, dopaminergic, sensory and retinal neurons. We will also discuss the hurdles that need to be overcome for clinical translation. |
| Publish Date |
2019-07-26 00:39 |
| Citation |
El Wazan L, Urrutia-Cabrera D, Wong RCB. Using transcription factors for direct reprogramming of neurons in vitro. World J Stem Cells 2019; 11(7): 431-444 |
| URL |
https://www.wjgnet.com/1948-0210/full/v11/i7/431.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v11.i7.431 |
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