Publication Name	World Journal of Gastroenterology
Manuscript ID	4686
Country	Italy

Received	2013-07-16 08:33
Peer-Review Started	2013-07-16 09:16
To Make the First Decision	2013-10-14 21:22
Return for Revision	2013-10-19 15:44
Revised	2013-11-05 01:03
Second Decision	2013-11-13 10:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-11-13 14:33
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-01-17 16:24
Typeset the Manuscript	2014-02-19 10:39
Publish the Manuscript Online	2014-02-26 11:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Longitudinal analysis of inflammation and microbiota dynamics in a model of mild chronic dextran sulfate sodium-induced colitis in mice
Manuscript Source	Invited Manuscript
All Author List	Luigia De Fazio, Elena Cavazza, Enzo Spisni, Antonio Strillacci, Manuela Centanni, Marco Candela, Chiara Praticò, Massimo Campieri, Chiara Ricci and Maria Chiara Valerii
Funding Agency and Grant Number	Funding Agency Grant Number Xeda international, France
Corresponding Author	Enzo Spisni, Professor, Department of Biological, Geological and Environmental Sciences, Biology Unit, University of Bologna, Via Selmi 3, 40126 Bologna, Italy. enzo.spisni@unibo.it
Key Words	Colitis; Dysbiosis; Dextran sulfate sodium; Inflammation; Cyclooxygenase 2
Core Tip	Experimental animal models of colitis are important for investigating the physiopathological mechanisms underlying inflammatory bowel disease (IBD) in humans. Murine dextran sulfate sodium colitis models have been widely adopted and validated as relevant models for the translation of mice data to human IBD. Nevertheless, it is clear that models characterized by mild intestinal damages are more accurate for studying the effects of therapeutic agents. In this study, we developed a reproducible mild chronic colitis model, which allows the evaluation of the intestinal repair processes, the modulation of systemic inflammation and the recovery of the gut microbiotic homeostasis.
Publish Date	2014-02-26 11:18
Citation	De Fazio L, Cavazza E, Spisni E, Strillacci A, Centanni M, Candela M, Praticò C, Campieri M, Ricci C, Valerii MC. Longitudinal analysis of inflammation and microbiota dynamics in a model of mild chronic dextran sulfate sodium-induced colitis in mice. World J Gastroenterol 2014; 20(8): 2051-2061
URL	http://www.wjgnet.com/1007-9327/full/v20/i8/2051.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i8.2051

Full Article (PDF)	WJG-20-2051.pdf
Full Article (Word)	WJG-20-2051.doc
Manuscript File	4686-Review.docx
Answering Reviewers	4686-Answering reviewers.pdf
Copyright License Agreement	4686-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	Cover letter.docx
Peer-review Report	4686-Peer review(s).pdf
Scientific Editor Work List	4686-Scientific editor work list.doc