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Articles Published Processes
9/7/2019 4:43:36 AM | Browse: 965 | Download: 1524
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Received |
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2019-05-18 05:31 |
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Peer-Review Started |
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2019-05-20 07:55 |
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To Make the First Decision |
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2019-07-22 03:33 |
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Return for Revision |
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2019-07-23 02:09 |
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Revised |
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2019-07-29 09:02 |
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Second Decision |
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2019-08-02 10:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-08-07 09:35 |
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Articles in Press |
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2019-08-07 09:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-04 03:22 |
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Publish the Manuscript Online |
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2019-09-07 04:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Helicobacter pylori virulence genes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Anja Šterbenc, Erika Jarc, Mario Poljak and Matjaž Homan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Matjaž Homan, MD, PhD, Assistant Professor, Department of Gastroenterology, Hepatology and Nutrition, University Children’s Hospital, Faculty of Medicine, University of Ljubljana, Bohoričeva 20, Ljubljana 1000, Slovenia. matjaz.homan@guest.arnes.si |
| Key Words |
Helicobacter pylori; Virulence genes; Disease association; Children; Adults; Outer membrane proteins |
| Core Tip |
The assessment of pathogenicity of a plethora of Helicobacter pylori (H. pylori) virulence genes appears to be relatively difficult. In specific, H. pylori isolates show a high degree of geographic variability, with certain H. pylori genotypes being associated with a more severe clinical outcome in some regions, while presenting as virtually harmless variants in other studied populations. To date, cagA and certain allelic variants of vacA have been most consistently associated with severe gastroduodenal disease in both children and adults, whereas the role of outer membrane proteins, such as babA2, sabA, homB and oipA, is somewhat more ambiguous. |
| Publish Date |
2019-09-07 04:43 |
| Citation |
Šterbenc A, Jarc E, Poljak M, Homan M. Helicobacter pylori virulence genes. World J Gastroenterol 2019; 25(33): 4870-4884 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i33/4870.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i33.4870 |
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