Publication Name	World Journal of Gastroenterology
Manuscript ID	49130
Country	Slovenia

Received	2019-05-18 05:31
Peer-Review Started	2019-05-20 07:55
To Make the First Decision	2019-07-22 03:33
Return for Revision	2019-07-23 02:09
Revised	2019-07-29 09:02
Second Decision	2019-08-02 10:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-08-07 09:35
Articles in Press	2019-08-07 09:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-09-04 03:22
Publish the Manuscript Online	2019-09-07 04:43

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Helicobacter pylori virulence genes
Manuscript Source	Invited Manuscript
All Author List	Anja Šterbenc, Erika Jarc, Mario Poljak and Matjaž Homan
ORCID	Author(s) ORCID Number Anja Šterbenc http://orcid.org/0000-0001-8522-3753 Erika Jarc http://orcid.org/0000-0001-8516-9179 Mario Poljak http://orcid.org/0000-0002-3216-7564 Matjaž Homan http://orcid.org/0000-0001-5764-5430
Funding Agency and Grant Number
Corresponding Author	Matjaž Homan, MD, PhD, Assistant Professor, Department of Gastroenterology, Hepatology and Nutrition, University Children’s Hospital, Faculty of Medicine, University of Ljubljana, Bohoričeva 20, Ljubljana 1000, Slovenia. matjaz.homan@guest.arnes.si
Key Words	Helicobacter pylori; Virulence genes; Disease association; Children; Adults; Outer membrane proteins
Core Tip	The assessment of pathogenicity of a plethora of Helicobacter pylori (H. pylori) virulence genes appears to be relatively difficult. In specific, H. pylori isolates show a high degree of geographic variability, with certain H. pylori genotypes being associated with a more severe clinical outcome in some regions, while presenting as virtually harmless variants in other studied populations. To date, cagA and certain allelic variants of vacA have been most consistently associated with severe gastroduodenal disease in both children and adults, whereas the role of outer membrane proteins, such as babA2, sabA, homB and oipA, is somewhat more ambiguous.
Publish Date	2019-09-07 04:43
Citation	Šterbenc A, Jarc E, Poljak M, Homan M. Helicobacter pylori virulence genes. World J Gastroenterol 2019; 25(33): 4870-4884
URL	https://www.wjgnet.com/1007-9327/full/v25/i33/4870.htm
DOI	https://dx.doi.org/10.3748/wjg.v25.i33.4870

Full Article (PDF)	WJG-25-4870.pdf
Full Article (Word)	WJG-25-4870.docx
Manuscript File	49130-Review.docx
Answering Reviewers	49130-Answering reviewers.pdf
Audio Core Tip	49130-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	49130-Conflict-of-interest statement.pdf
Copyright License Agreement	49130-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	49130-Language certificate.pdf
Peer-review Report	49130-Peer-review(s).pdf
Scientific Misconduct Check	49130-Scientific misconduct check.pdf
Scientific Editor Work List	49130-Scientific editor work list.pdf