ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Timing, distribution and microbiology of infectious complications after necrotizing pancreatitis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Lu Jiong Di, Cao Feng, Ding Yi Xuan, Wu Yu Duo, Guo Yu Lin and Fei Li |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
supported by Beijing Municipal Science &Technology Commission |
Z171100001017077 |
Beijing Municipal Administration of Hospitals Clinical medicine Development of special funding support |
XMLX201404 |
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Corresponding Author |
Fei Li, MD, PhD, Chief Doctor, Doctor, Doctor, Professor, Surgeon, general surgery, Xuanwu Hospital Capital Medical University, No.45 Changchun Street, Xicheng District,Beijing, Beijing 100053, China. feili36@ccmu.edu.cn |
Key Words |
Necrotizing pancreatitis; Extrapancreatic infection; Pathogenic bacteria; Drug sensitivity test; ; |
Core Tip |
In our study,gram-negative bacteria were the main pathogens in necrotizing pancreatitis patients with infectious complications in our hospital. The most common were Escherichia coli, Pseudomonas aeruginosa. Additionally, the proportion of multidrug-resistant bacteria was relatively large, and caution should be used in the application of antibiotics. The extrapancreatic infection time was usually earlier than that of pancreatic infection. For patients with suspected infection, blood and respiratory pathogens should be cultured first. Third or fourth generation cephalosporins or carbapenems can be used as empirical drugs. Persistent organ failure, multidrug resistance and a larger number of operations were risk factors for death. |
Publish Date |
2019-09-12 08:50 |
Citation |
Lu JD, Cao F, Ding YX, Wu YD, Guo YL, Li F. Timing, distribution and microbiology of infectious complications after necrotizing pancreatitis. World J Gastroenterol 2019; 25(34): 5162-5173 |
URL |
https://www.wjgnet.com/1007-9327/full/v25/i34/5162.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v25.i34.5162 |