| ISSN |
2218-6255 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019 Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Respiratory System |
| Manuscript Type |
Case Control Study |
| Article Title |
Relationship between metabolic syndrome and hypercapnia among obese patients with sleep apnea
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Yuka Kimura, Takatoshi Kasai, Yasuhiro Tomita, Satoshi Kasagi, Hisashi Takaya, Mitsue Kato, Fusae Kawana and Koji Narui |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Intractable Respiratory Diseases and Pulmonary Hypertension Research Group, from the Ministry of Health, Labor and Welfare |
H29-027 |
| Health, Labour and Welfare Sciences Research Grants, Research on Region Medical |
H30-iryou-ippan-009 |
| MEXT-Supported Program for the Strategic Research Foundation at Private Universities, 2014-2018 (Ministry of Education, Culture, Sports, Science and Technology) |
|
| JSPS KAKENHI |
JP17K09527 |
|
| Corresponding Author |
Takatoshi Kasai, MD, PhD, Associate Professor, Department of Cardiovascular Medicine, Cardiovascular Respiratory Sleep Medicine, Juntendo University Graduate School of Medicine; Sleep and Sleep Disordered Breathing Center, Juntendo University Hospital, 2-1-1 Hongo Bunkyo-ku, Tokyo 113-8421, Japan. kasai-t@mx6.nisiq.net |
| Key Words |
Arterial partial pressure of carbon dioxide; Hypercapnia; Metabolic syndrome; Obesity hypoventilation syndrome; Obstructive sleep apnea; Sleep disordered breathing |
| Core Tip |
Daytime hypercapnia presents with severe obstructive sleep apnea in some obese patients, and the condition is called obesity hypoventilation syndrome. However, the prevalence, characteristics, and other clinical features of hypercapnic obese patients with severe obstructive sleep apnea remain unelucidated. Among 97 obese patients with severe obstructive sleep apnea, 25 had daytime hypercapnia, and they were more likely to have the metabolic syndrome. In multivariable analysis, metabolic syndrome was associated with daytime hypercapnia. Although the cause or consequence remains unclear, coexisting metabolic syndrome may play some roles; thus, clinicians should check for metabolic syndrome in obese patients with severe obstructive sleep apnea. |
| Publish Date |
2019-12-27 08:14 |
| Citation |
Kimura Y, Kasai T, Tomita Y, Kasagi S, Takaya H, Kato M, Kawana F, Narui K. Relationship between metabolic syndrome and hypercapnia among obese patients with sleep apnea. World J Respirol 2020; 10(1): 1-10 |
| URL |
https://www.wjgnet.com/2218-6255/full/v10/i1/1.htm |
| DOI |
https://dx.doi.org/10.5320/wjr.v10.i1.1 |
