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Articles Published Processes
4/7/2020 2:46:34 PM | Browse: 732 | Download: 1238
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Received |
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2019-12-18 13:43 |
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Peer-Review Started |
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2019-12-18 13:44 |
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To Make the First Decision |
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Return for Revision |
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2020-02-18 23:04 |
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Revised |
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2020-03-05 14:10 |
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Second Decision |
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2020-03-09 14:58 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-03-09 17:41 |
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Articles in Press |
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2020-03-09 17:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-04-06 03:19 |
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Publish the Manuscript Online |
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2020-04-07 14:46 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Mouse models of colorectal cancer: Past, present and future perspectives
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Florian Bürtin, Christina S Mullins and Michael Linnebacher |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| State Mecklenburg-Vorpommern |
TBI-V-1-241-VBW-084 |
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| Corresponding Author |
Michael Linnebacher, PhD, Academic Fellow, Research Fellow, Research Scientist, Senior Researcher, Senior Scientist, Molecular Oncology and Immunotherapy, Department of General, Visceral, Vascular and Transplantation Surgery, University Medical Center Rostock, Schillingallee 69, Rostock 18057, Germany. michael.linnebacher@med.uni-rostock.de |
| Key Words |
Colorectal cancer; Mouse models; Patient-derived xenografts; Carcinogen-induced models; Genetically engineered mouse models; Preclinical drug development |
| Core Tip |
This review highlights the different approaches to model colorectal cancer in the mouse. Carcinogen-induced rodent models, genetically engineered mouse models, heterotopic and orthotopic models as well as patient-derived xenografts are discussed with an emphasis on their specific advantages and disadvantages. Moreover, the historical background of animal models for cancer research and the future perspectives of colorectal cancer research are reviewed as well. |
| Publish Date |
2020-04-07 14:46 |
| Citation |
Bürtin F, Mullins CS, Linnebacher M. Mouse models of colorectal cancer: Past, present and future perspectives. World J Gastroenterol 2020; 26(13): 1394-1426 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i13/1394.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i13.1394 |
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