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4/7/2020 2:46:34 PM | Browse: 616 | Download: 848
Publication Name World Journal of Gastroenterology
Manuscript ID 53411
Country/Territory Germany
Received
2019-12-18 13:43
Peer-Review Started
2019-12-18 13:44
To Make the First Decision
Return for Revision
2020-02-18 23:04
Revised
2020-03-05 14:10
Second Decision
2020-03-09 14:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-03-09 17:41
Articles in Press
2020-03-09 17:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-04-06 03:19
Publish the Manuscript Online
2020-04-07 14:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Mouse models of colorectal cancer: Past, present and future perspectives
Manuscript Source Invited Manuscript
All Author List Florian Bürtin, Christina S Mullins and Michael Linnebacher
ORCID
Author(s) ORCID Number
Florian Bürtin http://orcid.org/0000-0001-9927-1852
Christina S Mullins http://orcid.org/0000-0003-2296-2027
Michael Linnebacher http://orcid.org/0000-0001-8054-1402
Funding Agency and Grant Number
Funding Agency Grant Number
State Mecklenburg-Vorpommern TBI-V-1-241-VBW-084
Corresponding Author Michael Linnebacher, PhD, Academic Fellow, Research Fellow, Research Scientist, Senior Researcher, Senior Scientist, Molecular Oncology and Immunotherapy, Department of General, Visceral, Vascular and Transplantation Surgery, University Medical Center Rostock, Schillingallee 69, Rostock 18057, Germany. michael.linnebacher@med.uni-rostock.de
Key Words Colorectal cancer; Mouse models; Patient-derived xenografts; Carcinogen-induced models; Genetically engineered mouse models; Preclinical drug development
Core Tip This review highlights the different approaches to model colorectal cancer in the mouse. Carcinogen-induced rodent models, genetically engineered mouse models, heterotopic and orthotopic models as well as patient-derived xenografts are discussed with an emphasis on their specific advantages and disadvantages. Moreover, the historical background of animal models for cancer research and the future perspectives of colorectal cancer research are reviewed as well.
Publish Date 2020-04-07 14:46
Citation Bürtin F, Mullins CS, Linnebacher M. Mouse models of colorectal cancer: Past, present and future perspectives. World J Gastroenterol 2020; 26(13): 1394-1426
URL https://www.wjgnet.com/1007-9327/full/v26/i13/1394.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i13.1394
Full Article (PDF) WJG-26-1394.pdf
Full Article (Word) WJG-26-1394.docx
Manuscript File 53411-Review.docx
Answering Reviewers 53411-Answering reviewers.pdf
Audio Core Tip 53411-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 53411-Conflict-of-interest statement.pdf
Copyright License Agreement 53411-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 53411-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 53411-Language certificate.pdf
Peer-review Report 53411-Peer-review(s).pdf
Scientific Misconduct Check 53411-Scientific misconduct check.pdf
Scientific Editor Work List 53411-Scientific editor work list.pdf