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6/24/2020 7:33:17 AM | Browse: 690 | Download: 1502
Publication Name World Journal of Clinical Cases
Manuscript ID 55225
Country China
2020-03-08 07:57
Peer-Review Started
2020-03-08 07:57
To Make the First Decision
Return for Revision
2020-04-22 19:19
2020-05-18 16:37
Second Decision
2020-05-25 10:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-26 02:48
Articles in Press
2020-05-26 02:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-05-30 04:33
Typeset the Manuscript
2020-06-17 00:00
Publish the Manuscript Online
2020-06-24 07:33
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Case Report
Article Title Anti-N-methyl-D-aspartate-receptor antibody encephalitis combined with syphilis: A case report
Manuscript Source Unsolicited Manuscript
All Author List Xi-Yu Li, Zhi-Hong Shi, Ya-Lin Guan and Yong Ji
Author(s) ORCID Number
Xi-Yu Li http://orcid.org/0000-0002-2586-1187
Zhi-Hong Shi http://orcid.org/0000-0001-5235-6349
Ya-Lin Guan http://orcid.org/0000-0002-8892-8422
Yong Ji http://orcid.org/0000-0002-2191-6996
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81571057
Tianjin Science and Technology Project 16ZXMJSY00010
Corresponding Author Zhi-Hong Shi, MD, PhD, Chief Doctor, Tianjin Key Laboratory of Cerebrovascular and of neurodegenerative diseases, Tianjin dementia institute, Department of neurology, Tianjin Huanhu Hospital, No. 6 Ji Zhao Stree, Jinnan District, Tianjin 300350, China. shzhh1204@126.com
Key Words Anti-N-methyl-D-aspartate receptor encephalitis; Syphilis; Imaging manifestations; Treatment; Methylprednisolone; Immunoglobulin
Core Tip Anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis is a common type of autoimmune encephalitis characterized by complex clinical signs and various imaging manifestations. We present a rare case of anti-NMDAR encephalitis combined with syphilis, developing in a previously healthy immunocompetent male patient. Anti-NMDAR was detected in the cerebrospinal fluid. Our patient’s symptoms improved after methylprednisolone and immunoglobulin treatment. In order to avoid misdiagnosis and delay of treatment, this case emphasizes anti-NMDAR encephalitis can present in combination with syphilis. Second, the unique imaging manifestations of anti-NMDAR encephalitis and the clinical manifestations caused by the involvement of the pons, midbrain, and basal ganglia should be recognized.
Publish Date 2020-06-24 07:33
Citation Li XY, Shi ZH, Guan YL, Ji Y. Anti-N-methyl-D-aspartate-receptor antibody encephalitis combined with syphilis: A case report. World J Clin Cases 2020; 8(12): 2603-2609
URL https://www.wjgnet.com/2307-8960/full/v8/i12/2603.htm
DOI https://dx.doi.org/10.12998/wjcc.v8.i12.2603
Full Article (PDF) WJCC-8-2603.pdf
Full Article (Word) WJCC-8-2603.docx
CARE Checklist–2016 55225-CARE-Checklist–2016-revision.docx
Manuscript File 55225-Review_WangTQ.docx
Answering Reviewers 55225-Answering reviewers.pdf
Audio Core Tip 55225-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 55225-Conflict-of-interest statement.pdf
Copyright License Agreement 55225-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 55225-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 55225-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 55225-Language certificate.pdf
Peer-review Report 55225-Peer-review(s).pdf
Scientific Misconduct Check 55225-Bing-Zhang H-1.png
Scientific Misconduct Check 55225-Bing-Zhang L-2.png
Scientific Misconduct Check 55225-Scientific misconduct check.pdf
Scientific Editor Work List 55225-Scientific editor work list.pdf