Publication Name	World Journal of Stem Cells
Manuscript ID	5671
Country	United States

Received	2013-09-20 11:54
Peer-Review Started	2013-09-20 22:09
To Make the First Decision	2013-10-14 14:19
Return for Revision	2013-10-20 23:18
Revised	2013-10-29 05:31
Second Decision	2014-01-14 18:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-14 20:01
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-04-20 20:59
Publish the Manuscript Online	2014-04-28 14:14

ISSN	1948-0210 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Topic Highlights
Article Title	Enhancing the efficacy of mesenchymal stem cell therapy
Manuscript Source	Invited Manuscript
All Author List	Michalis Mastri, Huey Lin and Techung Lee
Funding Agency and Grant Number	Funding Agency Grant Number NIH R01HL84590 NYSTEM University at Buffalo Biomedical Research Service Center
Corresponding Author	Techung Lee, Associate Professor, Department of Biomedical Engineering, Center for Research in Cardiovascular Medicine, University at Buffalo, 140 Farber, 3435 Main Street, Buffalo, NY 14214, United States. chunglee@buffalo.edu
Key Words	Mesenchymal stem cell; Therapy; Clinical trial; Paracrine
Core Tip	Mesenchymal stem cell (MSC) therapy is entering a challenging phase after completion of many preclinical and clinical trials, and the focus is shifting from initial feasibility and safety studies to optimization of therapeutic strategies. Among the major hurdles encountered in MSC therapy are inconsistent stem cell potency, poor cell engraftment and survival, and age/disease-related host tissue impairment. The goal of this mini-review is to highlight several feasible and readily translatable approaches for boosting therapeutic potency and ultimately promoting the success of regenerative medicine.
Publish Date	2014-04-28 14:14
Citation	Mastri M, Lin H, Lee T. Enhancing the efficacy of mesenchymal stem cell therapy. World J Stem Cells 2014; 6(2): 82-93
URL	http://www.wjgnet.com/1948-0210/full/v6/i2/82.htm
DOI	http://dx.doi.org/10.4252/wjsc.v6.i2.82

Full Article (PDF)	WJSC-6-82.pdf
Full Article (Word)	WJSC-6-82.doc
Manuscript File	5671-Review.docx
Answering Reviewers	5671-Answering reviewers.pdf
Copyright License Agreement	5671-Copyright assignment.pdf
Peer-review Report	5671-Peer review(s).pdf
Scientific Editor Work List	5671-Scientific editor work list.doc