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9/15/2014 6:27:00 PM | Browse: 365 | Download: 348
Publication Name World Journal of Stem Cells
Manuscript ID 5671
Country/Territory United States
Received
2013-09-20 11:54
Peer-Review Started
2013-09-20 22:09
To Make the First Decision
2013-10-14 14:19
Return for Revision
2013-10-20 23:18
Revised
2013-10-29 05:31
Second Decision
2014-01-14 18:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-01-14 20:01
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-04-20 20:59
Publish the Manuscript Online
2014-04-28 14:14
ISSN 1948-0210 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research and Experimental
Manuscript Type Topic Highlights
Article Title Enhancing the efficacy of mesenchymal stem cell therapy
Manuscript Source Invited Manuscript
All Author List Michalis Mastri, Huey Lin and Techung Lee
Funding Agency and Grant Number
Funding Agency Grant Number
NIH R01HL84590
NYSTEM
University at Buffalo Biomedical Research Service Center
Corresponding author Techung Lee, Associate Professor, Department of Biomedical Engineering, Center for Research in Cardiovascular Medicine, University at Buffalo, 140 Farber, 3435 Main Street, Buffalo, NY 14214, United States. chunglee@buffalo.edu
Keywords Mesenchymal stem cell; Therapy; Clinical trial; Paracrine
Core Tip Mesenchymal stem cell (MSC) therapy is entering a challenging phase after completion of many preclinical and clinical trials, and the focus is shifting from initial feasibility and safety studies to optimization of therapeutic strategies. Among the major hurdles encountered in MSC therapy are inconsistent stem cell potency, poor cell engraftment and survival, and age/disease-related host tissue impairment. The goal of this mini-review is to highlight several feasible and readily translatable approaches for boosting therapeutic potency and ultimately promoting the success of regenerative medicine.
Publish Date 2014-04-28 14:14
Citation Mastri M, Lin H, Lee T. Enhancing the efficacy of mesenchymal stem cell therapy. World J Stem Cells 2014; 6(2): 82-93
Url http://www.wjgnet.com/1948-0210/full/v6/i2/82.htm
DOI http://dx.doi.org/10.4252/wjsc.v6.i2.82
Full Article (PDF) WJSC-6-82.pdf
Full Article (Word) WJSC-6-82.doc
Manuscript File 5671-Review.docx
Answering Reviewers 5671-Answering reviewers.pdf
Copyright License Agreement 5671-Copyright assignment.pdf
Peer-review Report 5671-Peer review(s).pdf
Scientific Editor Work List 5671-Scientific editor work list.doc