Publication Name	World Journal of Clinical Cases
Manuscript ID	59374
Country	China

Received	2020-09-14 01:32
Peer-Review Started	2020-09-08 03:11
To Make the First Decision
Return for Revision	2021-01-24 18:54
Revised	2021-01-27 07:41
Second Decision	2021-04-15 10:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-19 18:15
Articles in Press	2021-04-19 18:15
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-04-28 06:52
Typeset the Manuscript	2021-05-28 07:44
Publish the Manuscript Online	2021-06-11 09:22

ISSN	2307-8960 (online)
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Category	Genetics & Heredity
Manuscript Type	Case Report
Article Title	Alport syndrome combined with lupus nephritis in a Chinese family: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Hui-Fang Liu, Qing Li and You-Qun Peng
ORCID	Author(s) ORCID Number Hui-Fang Liu http://orcid.org/0000-0001-9096-6711 Qing Li http://orcid.org/0000-0002-5060-5580 You-Qun Peng http://orcid.org/0000-0001-5934-3479
Funding Agency and Grant Number	Funding Agency Grant Number the Science and Technology Bureau of Jiulongpo District in Chongqing 2019-02-027-D
Corresponding Author	You-Qun Peng, PhD, Professor, Department of Nephrology, Traditional Chinese Medicine Hospital of Jiulongpo District, No. 160 Yuquancun Street, Jiulongpo District , Chongqing 400050, China. 376452999@qq.com
Key Words	Alport syndrome; Lupus nephritis; COL4A3; Whole exome sequencing; Splicing site; Case report
Core Tip	Alport syndrome is a hereditary nephropathy and can be combined with other disease or syndrome. We present the case of a 33-year-old male who was initially diagnosed with lupus nephritis but further diagnosed with Alport syndrome after genetic testing. He achieved complete remission after treatment with hormone and immunosuppressive agent. A variant in the splicing site of intron 22 in the COL4A3 gene was identified by the whole exome sequencing, which was co-segregated with the phenotype in the pedigree.
Publish Date	2021-06-11 09:22
Citation	Liu HF, Li Q, Peng YQ. Alport syndrome combined with Lupus nephritis in a Chinese family: A case report. World J Clin Cases 2021; 9(18): 4721-4727
URL	https://www.wjgnet.com/2307-8960/full/v9/i18/4721.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i18.4721

Full Article (PDF)	WJCC-9-4721.pdf
Full Article (Word)	WJCC-9-4721.docx
CARE Checklist–2016	59374-CARE-Checklist–2016-revision.pdf
Manuscript File	59374_Auto_Edited_LM_WangTQ.docx
Answering Reviewers	59374-Answering reviewers.pdf
Audio Core Tip	59374-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	59374-Conflict-of-interest statement.pdf
Copyright License Agreement	59374-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	59374-Language certificate.pdf
Signed Informed Consent Form(s) or Document(s)	59374-Informed consent statement.pdf
Peer-review Report	59374-Peer-review(s).pdf
Scientific Misconduct Check	59374-Bing-Wang JL-1.jpg
Scientific Misconduct Check	59374-Scientific misconduct check.pdf
Scientific Editor Work List	59374-Scientific editor work list.pdf