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Articles Published Processes
1/20/2021 12:47:16 PM | Browse: 455 | Download: 697
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Received |
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2020-09-28 06:02 |
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Peer-Review Started |
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2020-09-28 06:02 |
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To Make the First Decision |
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Return for Revision |
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2020-11-10 01:43 |
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Revised |
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2020-11-20 13:19 |
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Second Decision |
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2020-12-07 10:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-12-10 19:03 |
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Articles in Press |
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2020-12-10 19:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-12-17 01:39 |
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Typeset the Manuscript |
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2021-01-12 15:10 |
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Publish the Manuscript Online |
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2021-01-20 12:47 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Case Report |
| Article Title |
Clinical cure and liver fibrosis reversal after postoperative antiviral combination therapy in hepatitis B-associated non-cirrhotic hepatocellular carcinoma: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xue-Ping Yu, Qi Lin, Zhi-Peng Huang, Wei-Shan Chen, Ming-Hui Zheng, Yi-Juan Zheng, Ju-Lan Li and Zhi-Jun Su |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Fujian Province |
2019J01593 |
| High-Level Talent Innovation Project of Quanzhou |
2018C067R |
| Science and Technology Innovation Joint Project of Fujian Province |
2019Y9048 |
| Youth Research Project of Fujian Provincial Health Commission |
2018-1-94 |
| Youth Research Project of Fujian Provincial Health Commission |
2018-1-95 |
| Science and Technology Project of Quanzhou |
2018Z074 |
| Science and Technology Project of Quanzhou |
2018Z069 |
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| Corresponding Author |
Zhi-Jun Su, N/A, Chief Doctor, Department of Infection Disease, First Hospital of Quanzhou Affiliated to Fujian Medical University, No. 250 East Street, Licheng District, Quanzhou 362000, Fujian Province, China. su2366@sina.com |
| Key Words |
Hepatocellular carcinoma; Hepatitis B virus; Entecavir; Pegylated interferon alfa-2b; Clinical cure; Case report |
| Core Tip |
Patients with hepatitis B virus infection can progress to liver failure, cirrhosis, and hepatocellular carcinoma (HCC); however, not all HCC originates from cirrhosis, and approximately 15%-20% of HCC cases still occur without cirrhosis. Most importantly, the treatment of non-cirrhotic HCC after surgery and whether the risk of recurrence can be reduced by combining immunomodulators are the urgent problems that need to be solved at present. Therefore, we report a case in which HCC still occurred after 16 years of antiviral therapy, and the combination of immunoregulator therapy after HCC resection achieved clinical cure and liver fibrosis reversal. |
| Publish Date |
2021-01-20 12:47 |
| Citation |
Yu XP, Lin Q, Huang ZP, Chen WS, Zheng MH, Zheng YJ, Li JL, Su ZJ. Clinical cure and liver fibrosis reversal after postoperative antiviral combination therapy in hepatitis B-associated non-cirrhotic hepatocellular carcinoma: A case report. World J Clin Cases 2021; 9(3): 714-721 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i3/714.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i3.714 |
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