| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
A biomarker study in Peruvian males with breast cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Carlos A Castaneda, Miluska Castillo, Luis A Bernabe, Joselyn Sanchez, Ebert Torres, Nancy Suarez, Katherine Tello, Hugo Fuentes, Jorge Dunstan, Miguel De La Cruz, Jose Manuel Cotrina, Julio Abugattas, Henry Guerra and Henry L Gomez |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Consejo Nacional de Ciencia, Tecnologia e Innovacion Tecnologica |
198-2015-FONDECYT |
|
| Corresponding Author |
Carlos A Castaneda, MD, MSc, Associate Research Scientist, Faculty of Health Sciences, Universidad Cientifica del Sur, Carr. Panamericana Sur 19, Villa El Salvador, Lima 15067, Peru. carloscastanedaaltamirano@yahoo.com |
| Key Words |
Male breast neoplasm; Androgen receptor; Tumor-infiltrating lymphocyte; Mismatch repair protein; PIK3CA mutation |
| Core Tip |
Most male breast cancers were estrogen receptor-positive, HER2-negative, androgen receptor (AR)-positive, and Luminal A phenotype. Loss of mismatch repair (MMR) and PIK3CA mutations was found in around 15% of the cases. AR was correlated with ER expression and without loss of MMR proteins. Stage and grade are prognostic features in Peruvian male breast cancer. |
| Publish Date |
2021-10-22 09:56 |
| Citation |
Castaneda CA, Castillo M, Bernabe LA, Sanchez J, Torres E, Suarez N, Tello K, Fuentes H, Dunstan J, De La Cruz M, Cotrina JM, Abugattas J, Guerra H, Gomez HL. A biomarker study in Peruvian males with breast cancer. World J Clin Oncol 2021; 12(10): 926-934 |
| URL |
https://www.wjgnet.com/2218-4333/full/v12/i10/926.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v12.i10.926 |