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Articles Published Processes
9/9/2021 9:23:46 AM | Browse: 473 | Download: 1033
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Received |
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2021-02-21 06:04 |
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Peer-Review Started |
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2021-02-21 06:07 |
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To Make the First Decision |
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Return for Revision |
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2021-05-13 23:54 |
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Revised |
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2021-05-18 01:15 |
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Second Decision |
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2021-07-27 03:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-27 07:38 |
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Articles in Press |
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2021-07-27 07:38 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-09-07 10:52 |
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Publish the Manuscript Online |
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2021-09-09 09:23 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Neutrophil kinetics and function after major trauma: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Liam DB Finlay, Andrew Conway Morris, Adam Deane and Alexander JT Wood |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Wellcome Trust |
WT 205214/Z/16/Z |
| National Health and Medical Research Council (Australia) |
APP1141870 |
| MRC Clinician Scientist Fellowship |
MR/V006118/1 |
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| Corresponding Author |
Alexander JT Wood, MBBS, PhD, Doctor, Doctor, Intensive Care Unit, Royal Melbourne Hospital, Intensive Care Unit Offices
Level 5, B Block
Royal Melbourne Hospital
300 Grattan Street
, Parkville 3052, Victoria, Australia. alex.wood1@unimelb.edu.au |
| Key Words |
Neutrophils; Multiple trauma; Immunophenotypes; Inflammation; Systemic inflammatory response syndrome; Intensive care units |
| Core Tip |
Major trauma results in complex immune dysfunction, with dysregulated pro- and anti-inflammatory processes presenting as clinical syndromes such as acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS). This review examines the role of neutrophils in immune dysfunction following major trauma requiring admission to the intensive care unit, with a focus on the kinetics of the neutrophil immunophenotype and how this correlates with clinical outcomes. This review also proposes new hypotheses as to the mechanisms of complications of immune dysfunction, including ARDS and MODS. |
| Publish Date |
2021-09-09 09:23 |
| Citation |
Finlay LD, Conway Morris A, Deane A, Wood AJ. Neutrophil kinetics and function after major trauma: A systematic review. World J Crit Care Med 2021; 10(5): 260-277 |
| URL |
https://www.wjgnet.com/2220-3141/full/v10/i5/260.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v10.i5.260 |
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California Corporate Number: 3537345
