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Articles Published Processes
12/15/2021 9:38:23 AM | Browse: 374 | Download: 672
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Received |
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2021-03-01 04:19 |
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Peer-Review Started |
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2021-03-01 04:21 |
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To Make the First Decision |
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Return for Revision |
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2021-07-15 03:02 |
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Revised |
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2021-07-29 18:45 |
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Second Decision |
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2021-11-02 03:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-11-03 01:23 |
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Articles in Press |
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2021-11-03 01:23 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-10-14 09:41 |
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Typeset the Manuscript |
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2021-12-10 00:21 |
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Publish the Manuscript Online |
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2021-12-15 09:38 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Review |
| Article Title |
Nuclear receptors modulate inflammasomes in the pathophysiology and treatment of major depressive disorder
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Han Wang, Wei-Jing Kan, Yuan Feng, Lei Feng, Yang Yang, Pei Chen, Jing-Jie Xu, Tian-Mei Si, Ling Zhang, Gang Wang and Jing Du |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
31650005 |
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| Corresponding Author |
Jing Du, PhD, Professor, The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, No. 5 Ankanghuton, Western City District
, Beijing 100088, China. 2648215772@qq.com |
| Key Words |
Major depressive disorder; Immune inflammation; Inflammasome; Nuclear receptors |
| Core Tip |
We summarize the evidence on nuclear receptors (NRs), such as glucocorticoid receptor, mineralocorticoid receptor, estrogen receptor, aryl hydrocarbon receptor, and peroxisome proliferator-activated receptor, in modulating inflammasome activity and depression-associated behaviors. This review provides evidence from an endocrine perspective to understand the role of activated NRs in the pathophysiology and treatment of major depressive disorder. Hopefully, the modulation of NRs with hormones and metabolites may become one of the key endocrinologic mechanisms for the development of novel therapeutics to increase the likelihood of therapeutic efficacy. |
| Publish Date |
2021-12-15 09:38 |
| Citation |
Wang H, Kan WJ, Feng Y, Feng L, Yang Y, Chen P, Xu JJ, Si TM, Zhang L, Wang G, Du J. Nuclear receptors modulate inflammasomes in the pathophysiology and treatment of major depressive disorder. World J Psychiatr 2021; 11(12): 1191-1205 |
| URL |
https://www.wjgnet.com/2220-3206/full/v11/i12/1191.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v11.i12.1191 |
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