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Articles Published Processes
4/15/2022 9:40:09 AM | Browse: 356 | Download: 656
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Received |
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2021-03-17 23:14 |
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Peer-Review Started |
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2021-03-17 23:19 |
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To Make the First Decision |
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Return for Revision |
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2021-05-03 04:57 |
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Revised |
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2021-05-15 21:57 |
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Second Decision |
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2022-03-23 06:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-03-27 07:01 |
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Articles in Press |
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2022-03-27 07:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-04-01 11:17 |
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Publish the Manuscript Online |
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2022-04-15 09:40 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Minireviews |
Article Title |
Vasoactive intestinal peptide secreting tumour: An overview
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Manuscript Source |
Invited Manuscript |
All Author List |
Esther Una Cidon |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Esther Una Cidon, MD, MSc, PhD, Doctor, Doctor, Department of Medical Oncology, University Hospitals Dorset, Medical Oncology Service, Royal Bournemouth Hospital, Castle Lane East, Bournemouth BH7 7DW, Dorset, United Kingdom. aunacid@hotmail.com |
Key Words |
VIPoma; Octreotide; Secretory diarrhoea; Multiple endocrine neoplasia; Vasoactive intestinal peptide; Vermer-Morrison syndrome |
Core Tip |
Vasoactive intestinal peptide (VIP) secreting tumour (VIPoma) is a rare functional neuroendocrine tumour that typically arises from pancreatic islet cells. It is usually sporadic but may present as part of the endocrine neoplasia type I syndrome in 5% of cases. Excessive VIP secretion produces a refractory secretory diarrhoea which left untreated will cause patient's death. The majority of VIPomas are malignant and have already metastasized at the time of diagnosis (60%), being the liver, or regional lymph nodes the most frequent site for metastases. Complete surgical resection is the only potentially curative treatment, however, surgical debulking may provide palliative benefit. Other palliative options include somatostatin analogues and recently the peptide receptor radionuclide therapy which has shown to be effective and well-tolerated. |
Publish Date |
2022-04-15 09:40 |
Citation |
Una Cidon E. Vasoactive intestinal peptide secreting tumour: An overview. World J Gastrointest Oncol 2022; 14(4): 808-819 |
URL |
https://www.wjgnet.com/1948-5204/full/v14/i4/808.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v14.i4.808 |
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