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        8/24/2021 2:07:00 AM | Browse: 610 | Download: 1629
    
    
        
        
    
        
            
                
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                    Received | 
                 
             
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        2021-03-13 13:33 | 
    
    
        
            
                
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        2021-03-13 13:36 | 
    
    
        
            
                
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                    To Make the First Decision | 
                 
             
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        2021-06-04 10:14 | 
    
    
        
            
                
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        2021-06-12 14:14 | 
    
    
        
            
                
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        2021-07-05 12:47 | 
    
    
        
            
                
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                    Accepted by Journal Editor-in-Chief | 
                 
             
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                    Accepted by Executive Editor-in-Chief | 
                 
             
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        2021-07-05 13:11 | 
    
    
        
            
                
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                    Articles in Press | 
                 
             
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        2021-07-05 13:11 | 
    
    
        
            
                
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                    Publication Fee Transferred | 
                 
             
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                    Edit the Manuscript by Language Editor | 
                 
             
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        2021-07-12 14:44 | 
    
    
        
            
                
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                    Typeset the Manuscript | 
                 
             
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        2021-08-17 02:22 | 
    
            
                
                    
                        
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                            Publish the Manuscript Online | 
                         
                     
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                2021-08-24 02:07 | 
            
        
        
            
                | ISSN | 
                2307-8960 (online) | 
            
            
                | Open Access | 
                This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ | 
            
            
                | Copyright | 
                © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. | 
            
                    
                        | Article Reprints | 
                        
                            For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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                | Permissions | 
                
                    For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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                | Publisher | 
                Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA | 
            
            
                | Website | 
                http://www.wjgnet.com | 
            
        
    
        | Category | 
        Gastroenterology & Hepatology | 
    
    
        | Manuscript Type | 
        Retrospective Study | 
    
    
        | Article Title | 
        
                    Novel model combined contrast-enhanced ultrasound with serology predicts hepatocellular carcinoma recurrence after hepatectomy
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        | Manuscript Source | 
        Unsolicited Manuscript | 
    
    
        | All Author List | 
        Hai-Bin Tu, Li-Hong Chen, Yu-Jie Huang, Si-Yi Feng, Jian-Ling Lin and Yong-Yi Zeng | 
    
            
                | ORCID | 
                
                    
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        | Funding Agency and Grant Number | 
        
                    
                        
                            
                                | Funding Agency | 
                                Grant Number | 
                             
                        
                        
                                    
                                        | Startup Fund for scientific research, Fujian Medical University | 
                                        2019QH1302 | 
                                     
                        
                     
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        | Corresponding Author | 
        Yong-Yi Zeng, MD, PhD, Professor, Department of Hepatobiliary Surgery, Mengchao Hepatobiliary Hospital of Fujian Medical University, No. 312 Xihong Road, Fuzhou 350025, Fujian Province, China. lamp197311@126.com | 
    
    
        | Key Words | 
        Hepatocellular carcinoma; Recurrence; Prediction; Contrast-enhanced ultrasound; Liver imaging reporting and data system; Alpha-fetoprotein | 
    
    
        | Core Tip | 
        This study aimed to construct and verify a non-invasive prediction model combining contrast-enhanced ultrasound with serology biomarkers to predict the early recurrence of hepatocellular carcinoma.Records of 292 Local patients of hepatocellular carcinoma (HCC) were selected for analysis. A nomogram predicting early recurrence (ER) named contrasted-enhanced ultrasound (CEUS) model, incorporating tumor diameter, preoperative alpha-fetoprotein level, and LIRADS, was developed. The model showed satisfactory results, the C-index was 0.762 (95%CI: 0.706–0.819). The calibration at 6 mo was desirable.The CEUS model enables the well-calibrated individualized prediction of ER before surgery and may represent a novel tool for biomarker research and individual counseling. | 
    
            
                | Publish Date | 
                2021-08-24 02:07 | 
            
    
        | Citation | 
        Tu HB, Chen LH, Huang YJ, Feng SY, Lin JL, Zeng YY. Novel model combined contrast-enhanced ultrasound with serology predicts hepatocellular carcinoma recurrence after hepatectomy . World J Clin Cases 2021; 9(24): 7009-7021 | 
    
            
                | URL | 
                https://www.wjgnet.com/2307-8960/full/v9/i24/7009.htm | 
            
            
                | DOI | 
                https://dx.doi.org/10.12998/wjcc.v9.i24.7009 | 
            
    
    
        
                
        
     
 
                 
             
         
        
    
        
        
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