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8/24/2021 2:07:00 AM | Browse: 355 | Download: 621
Publication Name World Journal of Clinical Cases
Manuscript ID 65420
Country China
Received
2021-03-13 13:33
Peer-Review Started
2021-03-13 13:36
To Make the First Decision
Return for Revision
2021-06-04 10:14
Revised
2021-06-12 14:14
Second Decision
2021-07-05 12:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-05 13:11
Articles in Press
2021-07-05 13:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-07-12 14:44
Typeset the Manuscript
2021-08-17 02:22
Publish the Manuscript Online
2021-08-24 02:07
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Novel model combined contrast-enhanced ultrasound with serology predicts hepatocellular carcinoma recurrence after hepatectomy
Manuscript Source Unsolicited Manuscript
All Author List Hai-Bin Tu, Li-Hong Chen, Yu-Jie Huang, Si-Yi Feng, Jian-Ling Lin and Yong-Yi Zeng
ORCID
Author(s) ORCID Number
Hai-Bin Tu http://orcid.org/0000-0003-4540-9937
Li-Hong Chen http://orcid.org/0000-0002-2124-8203
Yu-Jie Huang http://orcid.org/0000-0003-4307-8716
Si-Yi Feng http://orcid.org/0000-0001-6305-0337
Jian-Ling Lin http://orcid.org/0000-0002-6133-7024
Yong-Yi Zeng http://orcid.org/0000-0001-7441-4271
Funding Agency and Grant Number
Funding Agency Grant Number
Startup Fund for scientific research, Fujian Medical University 2019QH1302
Corresponding Author Yong-Yi Zeng, MD, PhD, Professor, Department of Hepatobiliary Surgery, Mengchao Hepatobiliary Hospital of Fujian Medical University, No. 312 Xihong Road, Fuzhou 350025, Fujian Province, China. lamp197311@126.com
Key Words Hepatocellular carcinoma; Recurrence; Prediction; Contrast-enhanced ultrasound; Liver imaging reporting and data system; Alpha-fetoprotein
Core Tip This study aimed to construct and verify a non-invasive prediction model combining contrast-enhanced ultrasound with serology biomarkers to predict the early recurrence of hepatocellular carcinoma.Records of 292 Local patients of hepatocellular carcinoma (HCC) were selected for analysis. A nomogram predicting early recurrence (ER) named contrasted-enhanced ultrasound (CEUS) model, incorporating tumor diameter, preoperative alpha-fetoprotein level, and LIRADS, was developed. The model showed satisfactory results, the C-index was 0.762 (95%CI: 0.706–0.819). The calibration at 6 mo was desirable.The CEUS model enables the well-calibrated individualized prediction of ER before surgery and may represent a novel tool for biomarker research and individual counseling.
Publish Date 2021-08-24 02:07
Citation Tu HB, Chen LH, Huang YJ, Feng SY, Lin JL, Zeng YY. Novel model combined contrast-enhanced ultrasound with serology predicts hepatocellular carcinoma recurrence after hepatectomy . World J Clin Cases 2021; 9(24): 7009-7021
URL https://www.wjgnet.com/2307-8960/full/v9/i24/7009.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i24.7009
Full Article (PDF) WJCC-9-7009.pdf
Full Article (Word) WJCC-9-7009.docx
Manuscript File 65420_Auto_Edited-ZMG_WangTQ.docx
Answering Reviewers 65420-Answering reviewers.pdf
Audio Core Tip 65420-Audio core tip.mp3
Biostatistics Review Certificate 65420-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 65420-Conflict-of-interest statement.pdf
Copyright License Agreement 65420-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 65420-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 65420-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 65420-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 65420-Language certificate.pdf
Peer-review Report 65420-Peer-review(s).pdf
Scientific Misconduct Check 65420-Scientific misconduct check.pdf
Scientific Editor Work List 65420-Scientific editor work list.pdf