Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	65491
Country	United States

Received	2021-03-08 22:47
Peer-Review Started	2021-03-08 22:53
To Make the First Decision
Return for Revision	2021-03-29 17:05
Revised	2021-04-14 02:19
Second Decision	2022-04-15 02:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-04-16 14:36
Articles in Press	2022-04-16 14:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-27 12:25
Publish the Manuscript Online	2022-05-10 09:43

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Gut microbiome in non-alcoholic fatty liver disease associated hepatocellular carcinoma: Current knowledge and potential for therapeutics
Manuscript Source	Invited Manuscript
All Author List	Imaad Said, Hassan Ahad and Adnan Said
ORCID	Author(s) ORCID Number Imaad Said http://orcid.org/0000-0002-7126-3794 Hassan Ahad http://orcid.org/0000-0002-2527-6308 Adnan Said http://orcid.org/0000-0001-9944-4071
Funding Agency and Grant Number
Corresponding Author	Adnan Said, FAASLD, MD, MS, Associate Professor, Division of Gastroenterology and Hepatology, Department of Medicine, William S. Middleton VAMC, University of Wisconsin School of Medicine and Public Health, 4223 MFCB, 1685 Highland Avenue, Madison, WI 53705, United States. axs@medicine.wisc.edu
Key Words	Microbiome; Gut microbiome; Hepatocellular carcinoma; Nonalcoholic fatty liver disease; Pathophysiology; Treatment
Core Tip	The gut microbiome is intimately linked to nonalcoholic fatty liver disease, cirrhosis and hepatocellular carcinoma. The breakdown of the intestinal barrier in liver disease, innate immune system stimulation and bile acid profile changes are increasingly found in association with these diseases. Manipulation of the microbiome by diet, probiotics, prebiotics and other agents is a promising area of investigation.
Publish Date	2022-05-10 09:43
Citation	Said I, Ahad H, Said A. Gut microbiome in non-alcoholic fatty liver disease associated hepatocellular carcinoma: Current knowledge and potential for therapeutics. World J Gastrointest Oncol 2022; 14(5): 947-958
URL	https://www.wjgnet.com/1948-5204/full/v14/i5/947.htm
DOI	https://dx.doi.org/10.4251/wjgo.v14.i5.947

Full Article (PDF)	WJGO-14-947.pdf
Full Article (Word)	WJGO-14-947.docx
Manuscript File	65491_Auto_Edited_LM.docx
Answering Reviewers	65491-Answering reviewers.pdf
Audio Core Tip	65491-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	65491-Conflict-of-interest statement.pdf
Copyright License Agreement	65491-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	65491-Language certificate.pdf
Peer-review Report	65491-Peer-review(s).pdf
Scientific Misconduct Check	65491-Bing-Liu M-1.png
Scientific Misconduct Check	65491-Bing-Wu YXJ-2.jpg
Scientific Editor Work List	65491-Scientific editor work list.pdf