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Articles Published Processes
11/26/2021 5:51:27 PM | Browse: 515 | Download: 924
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Received |
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2021-07-18 04:21 |
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Peer-Review Started |
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2021-07-18 04:25 |
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To Make the First Decision |
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Return for Revision |
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2021-08-17 23:24 |
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Revised |
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2021-08-29 06:55 |
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Second Decision |
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2021-09-13 02:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-09-17 00:37 |
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Articles in Press |
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2021-09-17 00:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-11-23 01:55 |
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Publish the Manuscript Online |
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2021-11-26 17:51 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Patients with Clostridium difficile infection and prior appendectomy may be prone to worse outcomes
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Danial Haris Shaikh, Harish Patel, Rezwan Munshi, Haozhe Sun, Shehriyar Mehershahi, Ahmed Baiomi, Ahmed Alemam, Usman Pirzada, Iqra Nawaz, Kamrun Naher, Siddarth Hanumanthu and Suresh Nayudu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Danial Haris Shaikh, MD, Doctor, Doctor, Division of Gastroenterology, Department of Medicine, BronxCare Health System, 1650 Grand Concourse, Bronx, NY 10457, United States. dshaikh@bronxcare.org |
| Key Words |
Appendectomy; Clostridium difficile; Toxic megacolon; Colectomy; Gut microbiome |
| Core Tip |
Clostridium difficile infection occurs due to a dysbiosis of the gut. The appendix is known to host immune tissue and favorable gut microbiota, which may indirectly influence the disease course and outcomes in Clostridium difficile infection. We found that prior appendectomy may affect the severity of Clostridium difficile infection, and it may also increase the risk of developing toxic megacolon or requiring colectomy in these patients. Thus, earlier implementation of advanced therapeutic options may be necessary in patients without an appendix who develop Clostridium difficile infection. |
| Publish Date |
2021-11-26 17:51 |
| Citation |
Shaikh DH, Patel H, Munshi R, Sun H, Mehershahi S, Baiomi A, Alemam A, Pirzada U, Nawaz I, Naher K, Hanumanthu S, Nayudu S. Patients with Clostridium difficile infection and prior appendectomy may be prone to worse outcomes. World J Gastrointest Surg 2021; 13(11): 1436-1447 |
| URL |
https://www.wjgnet.com/1948-9366/full/v13/i11/1436.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v13.i11.1436 |
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