Publication Name	World Journal of Clinical Cases
Manuscript ID	70580
Country	China

Received	2021-08-07 13:12
Peer-Review Started	2021-08-07 13:14
To Make the First Decision
Return for Revision	2021-11-08 04:01
Revised	2021-12-11 05:10
Second Decision	2022-06-24 03:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-06-24 19:45
Articles in Press	2022-06-24 19:45
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-06-20 09:26
Typeset the Manuscript	2022-07-07 11:50
Publish the Manuscript Online	2022-08-16 01:35

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Exome analysis for Cronkhite-Canada syndrome: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Zhao-Dong Li, Li Rong, Yuan-Jing He, Yu-Zhu Ji, Xiang Li, Fang-Zhou Song and Xiao-An Li
ORCID	Author(s) ORCID Number Zhao-Dong Li http://orcid.org/0000-0002-3074-0611 Yu-Zhu Ji http://orcid.org/0000-0003-2563-8118 Xiang Li http://orcid.org/0000-0003-1363-1111 Xiao-An Li http://orcid.org/0000-0001-6128-6813
Funding Agency and Grant Number
Corresponding Author	Xiao-An Li, MD, Chief Doctor, Department of Gastroenterology,Mianyang Central Hospital, Mianyang Central Hospital, Department of Gastroenterology,Mianyang Central Hospital,12#Jingzhong Road, Fucheng District, Mianyang City, Sichuang, 621000 P.R. China; , mianyang city 621000, China. 435445611@qq.com
Key Words	Whole exome sequencing; Cronkhite-Canada syndrome; Somatic mutations; Case report
Core Tip	Cronkhite-Canada syndrome (CCS) is a rare, non-genetic disorder characterized by multiple gastrointestinal polyps, ectodermal lesions including alopecia, fingernail atrophy, and skin mucosal pigmentation. However, its pathogenesis is unclear. We performed exome sequencing in an elderly female patient and obtained somatic mutations in the hope that these data could provide a genetic perspective on the pathogenesis of CCS.
Publish Date	2022-08-16 01:35
Citation	Li ZD, Rong L, He YJ, Ji YZ, Li X, Song FZ, Li XA. Exome analysis for Cronkhite-Canada syndrome: A case report. World J Clin Cases 2022; 10(24): 8634-8640
URL	https://www.wjgnet.com/2307-8960/full/v10/i24/8634.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i24.8634

Full Article (PDF)	WJCC-10-8634.pdf
Full Article (Word)	WJCC-10-8634.docx
CARE Checklist–2016	70580-CARE-Checklist–2016-revision.pdf
Manuscript File	70580_Auto_Edited-LM.docx
Answering Reviewers	70580-Answering reviewers.pdf
Audio Core Tip	70580-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	70580-Conflict-of-interest statement.pdf
Copyright License Agreement	70580-Copyright license agreement.docx
Signed Consent for Treatment Form(s) or Document(s)	70580-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	70580-Language certificate.pdf
Supplementary Material	70580-Supplementary material.pdf
Peer-review Report	70580-Peer-review(s).pdf
Scientific Misconduct Check	70580-Bing-Ma YJ-2.png
Scientific Editor Work List	70580-Scientific editor work list.pdf
CrossCheck Report	70580-CrossCheck Report.pdf