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Articles Published Processes
4/8/2022 12:06:55 PM | Browse: 530 | Download: 1407
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Received |
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2021-08-09 06:46 |
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Peer-Review Started |
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2021-08-09 06:49 |
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First Decision by Editorial Office Director |
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2021-11-06 07:50 |
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Return for Revision |
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2021-11-06 07:50 |
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Revised |
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2021-11-23 09:04 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-02-25 06:33 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-02-27 19:49 |
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Articles in Press |
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2022-02-27 19:49 |
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Edit the Manuscript by Language Editor |
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2022-02-09 17:43 |
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Typeset the Manuscript |
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2022-03-14 04:43 |
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Publish the Manuscript Online |
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2022-04-08 12:06 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Case Report |
| Article Title |
Young children with multidrug-resistant epilepsy and vagus nerve stimulation responding to perampanel: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hua Yang and Dan Yu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dan Yu, MD, Doctor, Doctor, Professor, Department of Pediatrics, West China Second University Hospital, Sichuan University, No. 20, Section 3, South Renmin Road, Chengdu 610041, Sichuan Province, China. yudan540@163.com |
| Key Words |
Perampanel; Young children; Drug-resistant epilepsy; Vagus nerve stimulation; Case report |
| Core Tip |
We report a 4-year-old boy with multidrug-resistant epilepsy who still had frequent seizures after vagus nerve stimulation (VNS) implantation, and he showed significant response to perampanel (PER) as add-on in a dose-dependent manner. Considering its favorable cognitive profile and the similar efficacy and safety profile of PER in children aged < 12 years as in older people, we proposed that the use of PER as add-on could further reduce the seizure frequency for young children with drug-resistant epilepsy and even after VNS implantation, which may be attributed to its novel antiepileptic mechanism. |
| Publish Date |
2022-04-08 12:06 |
| Citation |
Yang H, Yu D. Young children with multidrug-resistant epilepsy and vagus nerve stimulation responding to perampanel: A case report. World J Clin Cases 2022; 10(11): 3511-3517 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i11/3511.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i11.3511 |
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