Publication Name	World Journal of Clinical Cases
Manuscript ID	73545
Country	China

Received	2022-01-09 12:20
Peer-Review Started	2022-01-09 12:21
To Make the First Decision
Return for Revision	2022-02-21 06:47
Revised	2022-03-03 15:07
Second Decision	2022-03-25 06:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-03-26 21:09
Articles in Press	2022-03-26 21:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-26 12:42
Publish the Manuscript Online	2022-05-13 08:46

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Case Report
Article Title	PD-1 inhibitor in combination with fruquintinib therapy for initial unresectable colorectal cancer: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Hong-Qiang Zhang, Chang-Zhi Huang, Jing-Yu Wu, Zhen-Ling Wang, Yu Shao and Zan Fu
ORCID	Author(s) ORCID Number Hong-Qiang Zhang http://orcid.org/0000-0002-7410-6911 Chang-Zhi Huang http://orcid.org/0000-0003-2620-9817 Jing-Yu Wu http://orcid.org/0000-0001-9366-5906 Zhen-Ling Wang http://orcid.org/0000-0002-6834-8607 Yu Shao http://orcid.org/0000-0001-8718-3193 Zan Fu http://orcid.org/0000-0003-4753-1821
Funding Agency and Grant Number
Corresponding Author	Zan Fu, MD, Chief Doctor, Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Nanjing 210029, Jiangsu Province, China. fuzan1971@njmu.edu.cn
Key Words	Colorectal cancer; Neoadjuvant; PD-1 inhibitors; Fruquintinib; MSI-H; Case report
Core Tip	A 30-year-old man was diagnosed with microsatellite unstable colon cancer. Prior to his surgical treatment, he was treated with a neoadjuvant regimen of PD1 inhibitors in combination with fruquintinib. This neoadjuvant regimen is rarely used; however, this patient had a good outcome. Subsequently, we performed a laparoscopic radical resection of his right colon cancer, which revealed no microscopic tumour cells. The patient was in good condition after the surgical treatment.
Publish Date	2022-05-13 08:46
Citation	Zhang HQ, Huang CZ, Wu JY, Wang ZL, Shao Y, Fu Z. PD-1 inhibitor in combination with fruquintinib therapy for initial unresectable colorectal cancer: A case report. World J Clin Cases 2022; 10(14): 4669-4675
URL	https://www.wjgnet.com/2307-8960/full/v10/i14/4669.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i14.4669

Full Article (PDF)	WJCC-10-4669.pdf
Full Article (Word)	WJCC-10-4669.docx
CARE Checklist–2016	73545-CARE-Checklist–2016-revision.pdf
Manuscript File	73545_Auto_Edited.docx
Answering Reviewers	73545-Answering reviewers.pdf
Audio Core Tip	73545-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	73545-Conflict-of-interest statement.pdf
Copyright License Agreement	73545-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	73545-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	73545-Language certificate.pdf
Peer-review Report	73545-Peer-review(s).pdf
Scientific Misconduct Check	73545-Bing-Wang LL-2.png
Scientific Editor Work List	73545-Scientific editor work list.pdf