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Articles Published Processes
6/9/2022 7:17:55 AM | Browse: 407 | Download: 994
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Received |
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2022-01-05 07:53 |
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Peer-Review Started |
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2022-01-05 07:55 |
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To Make the First Decision |
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Return for Revision |
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2022-01-27 17:23 |
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Revised |
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2022-01-30 10:59 |
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Second Decision |
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2022-04-02 02:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-04-03 22:31 |
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Articles in Press |
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2022-04-03 22:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-05-25 08:58 |
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Publish the Manuscript Online |
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2022-06-09 07:17 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Minireviews |
| Article Title |
Occult hepatitis B — the result of the host immune response interaction with different genomic expressions of the virus
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| Manuscript Source |
Invited Manuscript |
| All Author List |
George Sebastian Gherlan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
George Sebastian Gherlan, MD, PhD, Lecturer, Department of Infectious Diseases, “Carol Davila” University of Medicine and Pharmacy, 281 Mihai Bravu Street, Bucharest 030303, Romania. george.gherlan@umfcd.ro |
| Key Words |
Hepatitis B virus; Occult hepatitis B; Covalently closed circular DNA; Epigenetic factors; Immune factors; MicroRNA |
| Core Tip |
Every year, our knowledge of occult hepatitis B infection becomes richer with new information. This review is an up-to-date analysis of the viral and host factors that interact and lead to an occult form of hepatitis B virus infection. The latest discoveries in microRNA involvement, epigenetic mechanisms, immune system factors, and viral variants have been included for a comprehensive understanding of this challenging problem. We emphasize that occult hepatitis B infection is not only and not primarily a virus-driven condition; host immune and epigenetic mechanisms are also its important determinants. |
| Publish Date |
2022-06-09 07:17 |
| Citation |
Gherlan GS. Occult hepatitis B — the result of the host immune response interaction with different genomic expressions of the virus. World J Clin Cases 2022; 10(17): 5518-5530 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i17/5518.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i17.5518 |
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