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Articles Published Processes
7/27/2022 1:17:37 PM | Browse: 428 | Download: 960
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Received |
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2022-01-17 12:08 |
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Peer-Review Started |
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2022-01-17 12:09 |
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To Make the First Decision |
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Return for Revision |
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2022-03-08 10:13 |
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Revised |
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2022-04-20 13:48 |
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Second Decision |
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2022-07-01 03:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-07-06 04:48 |
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Articles in Press |
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2022-07-06 04:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-07-18 00:30 |
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Publish the Manuscript Online |
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2022-07-27 13:17 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Small extracellular vesicles and liver diseases: From diagnosis to therapy
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Manuscript Source |
Invited Manuscript |
All Author List |
Atsunori Tsuchiya, Kazuki Natsui, Yui Ishii, Yohei Koseki, Nobutaka Takeda, Kei Tomiyoshi, Fusako Yamazaki, Yuki Yoshida and Shuji Terai |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Atsunori Tsuchiya, MD, PhD, Associate Professor, Doctor, Doctor, Division of Gastroenterology and Hepatology, Niigata University Medical and Dental Hospital, 1-757 Asahimachi-dori, Chuo-ku, Niigata 951-8510, Japan. atsunori@med.niigata-u.ac.jp |
Key Words |
Small extracellular vesicles; Liver; cirrhosis; Hepatocellular carcinoma; Mesenchymal stem cells |
Core Tip |
Extracellular vesicles (EVs), especially small EVs (sEVs) derived from liver cells, have been the focus of much attention in the normal physiology and pathogenesis of various diseases affecting the liver. sEVs are approximately 100 nm in size, enclosed within lipid bilayers, and are very stable. The proteins and nucleic acids, including miRNAs, contained within these vesicles are known to play important roles in intercellular communication. This mini-review summarizes the application of sEVs in the diagnosis of liver diseases, along with their distribution post administration, their role in pathogenesis, and their potential therapeutic effects in hepatic disorders. |
Publish Date |
2022-07-27 13:17 |
Citation |
Tsuchiya A, Natsui K, Ishii Y, Koseki Y, Takeda N, Tomiyoshi K, Yamazaki F, Yoshida Y, Terai S. Small extracellular vesicles and liver diseases: From diagnosis to therapy. World J Hepatol 2022;14(7): 1307-1318 |
URL |
https://www.wjgnet.com/1948-5182/full/v14/i7/1307.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v14.i7.1307 |
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