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8/25/2014 10:03:00 AM | Browse: 441 | Download: 432
Publication Name World Journal of Diabetes
Manuscript ID 7681
Country/Territory Brazil
Received
2013-11-30 11:14
Peer-Review Started
2013-11-30 11:58
To Make the First Decision
2014-02-13 16:13
Return for Revision
2014-02-19 21:50
Revised
Second Decision
2014-03-18 14:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-03-18 15:15
Articles in Press
2014-05-23 09:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-03-27 23:59
Typeset the Manuscript
2014-06-13 21:01
Publish the Manuscript Online
2014-06-16 15:44
ISSN 1948-9358 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac and Cardiovascular Systems
Manuscript Type Topic Highlights
Article Title Impact of hypoglycemic agents on myocardial ischemic preconditioning
Manuscript Source Invited Manuscript
All Author List Rosa Maria Rahmi Garcia, Paulo Cury Rezende and Whady Hueb
Funding Agency and Grant Number
Funding Agency Grant Number
Zerbini Foundation
Corresponding author Whady Hueb, MD, PhD, MASS Study Group, Heart Institute of the University of S?o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 44, AB, Sala 114, Cerqueira Cesar, S?o Paulo 05403-000, Brazil. mass@incor.usp.br
Keywords Ischemic preconditioning; Myocardial ischemia; Coronary artery disease; Hypoglycemic agents; Diabetes mellitus
Core Tip Ischemic preconditioning (IP) is a complex phenomenon that can be the target of drug activities affecting the ability of the heart to adapt to ischemic stress. The literature contains conflicting results regarding whether the use of hypoglycemic agents interfere on cardiovascular mortality. Findings from studies about the effects of hypoglycemic drugs on IP have implications for diabetic patients, especially for those with high risk of events. Their results infer that myocardium can be benefited or not from the action of such drugs. Thus, therapeutic options go beyond glucose-lowering efficacy and should also ponder possible implications with mechanisms of myocardial protection.
Publish Date 2014-06-16 15:44
Citation Rahmi Garcia RM, Rezende PC, Hueb W. Impact of hypoglycemic agents on myocardial ischemic preconditioning. World J Diabetes 2014; 5(3): 258-266
Url http://www.wjgnet.com/1948-9358/full/v5/i3/258.htm
DOI http://dx.doi.org/10.4239/wjd.v5.i3.258
Full Article (PDF) WJD-5-258.pdf
Full Article (Word) WJD-5-258.doc
Manuscript File 7681-Review.docx
Answering Reviewers 7681-Answering reviewers.pdf
Copyright License Agreement 7681-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 7681-Language certificate.pdf
Peer-review Report 7681-Peer review(s).pdf
Scientific Editor Work List 7681-Scientific editor work list.doc